23112-96-1 Usage
Description
2,6-Dimethoxyphenylboronic acid is an organic compound with the chemical formula C8H11BO4, featuring a boron atom bonded to a phenyl ring with two methoxy groups at the 2nd and 6th positions. It is a white to beige powder and is commonly used as a reagent in various chemical reactions due to its unique chemical properties.
Uses
Used in Chemical Synthesis:
2,6-Dimethoxyphenylboronic acid is used as a reagent for the palladium-catalyzed Suzuki-Miyaura coupling reaction, which is a widely employed method for constructing carbon-carbon bonds in organic chemistry. This reaction is particularly useful in the synthesis of complex organic molecules and pharmaceutical compounds.
Used in Pharmaceutical Industry:
2,6-Dimethoxyphenylboronic acid is used as a reactant in the synthesis of 2H-imidazo[1,5-a]pyridin-4-ium bromides. These compounds serve as precursors for the preparation of N-heterocyclic carbene (NHC) ligands, which are essential in various pharmaceutical applications, including the development of new drugs and catalysts.
Used in Enzyme Inhibition:
2,6-Dimethoxyphenylboronic acid is also used in the preparation of monosubstituted benzothiazoloquinazolinones, which have potential as inhibitors of monoamine oxidases (MAO). These enzymes are involved in the breakdown of neurotransmitters, and their inhibition can be beneficial in treating various neurological and psychiatric disorders.
Used in Suzuki-Miyaura Reactions:
As a reactant, 2,6-Dimethoxyphenylboronic acid plays a crucial role in Suzuki-Miyaura reactions, which are cross-coupling reactions between an organoboronic compound and an organic halide or triflate. These reactions are widely used in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 23112-96-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,1 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23112-96:
(7*2)+(6*3)+(5*1)+(4*1)+(3*2)+(2*9)+(1*6)=71
71 % 10 = 1
So 23112-96-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H11BO4/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5,10-11H,1-2H3
23112-96-1Relevant articles and documents
A practical and scaleable synthesis of A-224817.0, a novel nonsteroidal ligand for the glucocorticoid receptor
Ku, Yi-Yin,Grieme, Tim,Raje, Prasad,Sharma, Padam,Morton, Howard E.,Rozema, Mike,King, Steve A.
, p. 3238 - 3240 (2003)
A practical and scaleable synthesis of a novel nonsteroidal ligand for the glucocorticoid receptor A-224817.0 1A is described. The synthesis proceeds in seven steps starting from 1,3-dimethoxybenzene. The biaryl intermediate 5 was prepared by an optimized
Kolbe-Schmitt type reaction under ambient conditions mediated by an organic base
Sadamitsu, Yuta,Okumura, Akira,Saito, Kodai,Yamada, Tohru
supporting information, p. 9837 - 9840 (2019/08/20)
The combined use of an organic base for resorcinols realized a Kolbe-Schmitt type reaction under ambient conditions. When resorcinols (3-hydroxyphenol derivatives) were treated with DBU under a carbon dioxide atmosphere, nucleophilic addition to carbon dioxide proceeded to afford the corresponding salicylic acid derivatives in high yields.
Novel organic compounds for organic light-emitting diode and organic light-emitting diode including the same
-
Paragraph 0097-0098, (2018/02/22)
The present invention relates to a compound for organic light-emitting diodes that can operate organic light-emitting diodes at a low driving voltage and an organic light-emitting diode comprising the same and, more particularly, to a compound for use as a fluorescent host in organic light-emitting diodes, which can bring about excellent diode properties by operating organic light-emitting diodes at a low driving voltage, and an organic light-emitting diode comprising the same.