23724-93-8 Usage
Description
1-Methoxyisoquinoline is a chemical compound characterized by the molecular formula C10H9NO, featuring an isoquinoline ring system with a methoxy group attached at the 1-position. It presents as a pale yellow to amber-colored liquid with a boiling point of 256°C. 1-Methoxyisoquinoline is recognized for its potential pharmacological properties, such as antimicrobial, antioxidant, and anti-inflammatory effects, and has been considered for the treatment of various medical conditions including Alzheimer's disease and cancer. Furthermore, 1-Methoxyisoquinoline serves as a precursor in the synthesis of other significant chemical compounds and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
1-Methoxyisoquinoline is used as a precursor for the synthesis of other important chemical compounds and pharmaceuticals, due to its versatile chemical structure and potential to be modified for specific therapeutic applications.
Used in Antimicrobial Applications:
1-Methoxyisoquinoline is utilized as an antimicrobial agent for its ability to combat various microorganisms, which can be beneficial in the development of new antibiotics or disinfectants.
Used in Antioxidant Applications:
As an antioxidant, 1-Methoxyisoquinoline is employed to neutralize free radicals, potentially protecting cells from oxidative damage and contributing to the development of treatments for conditions associated with oxidative stress.
Used in Anti-Inflammatory Applications:
1-Methoxyisoquinoline is used as an anti-inflammatory agent, leveraging its capacity to reduce inflammation, which can be instrumental in the management of inflammatory diseases.
Used in Alzheimer's Disease Treatment Research:
1-Methoxyisoquinoline is studied for its potential use in the treatment of Alzheimer's disease, possibly due to its neuroprotective properties or its ability to target specific pathological mechanisms associated with the condition.
Used in Cancer Treatment Research:
1-Methoxyisoquinoline is explored for its potential role in cancer treatment, with research focusing on its ability to target cancer cells, inhibit tumor growth, or enhance the effectiveness of existing cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 23724-93-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,2 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23724-93:
(7*2)+(6*3)+(5*7)+(4*2)+(3*4)+(2*9)+(1*3)=108
108 % 10 = 8
So 23724-93-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO/c1-12-10-9-5-3-2-4-8(9)6-7-11-10/h2-7H,1H3
23724-93-8Relevant articles and documents
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Albert,Phillips
, p. 1294,1399 (1956)
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Paquette et al.
, p. 3600 (1968)
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On the thermally induced rearrangement of 2-alkoxypyridines to N-alkylpyridones
Lister, Troy,Prager, Rolf H.,Tsaconas, Michael,Wilkinson, Kerry L.
, p. 913 - 916 (2007/10/03)
Analogues of 2-methoxypyridine undergo rearrangement to N-methylpyridones under flash vacuum pyrolysis (FVP) conditions. Ethoxy derivatives undergo competitive ethyl migration and elimination of ethylene. Analogues of 4-methoxypyridine do not undergo rearrangement under FVP conditions, but demethylation on silica may occur. The ease of rearrangement follows the basicity of the alkoxyhetarene to some extent. The vapour-phase rearrangements have been contrasted to condensed-phase pyrolyses. and a four-centre transition state for the former is supported by computation. The rearrangement allows structural assignment to the two products from the reaction of 2,4-dichloroquinoline with pyrrolidine.
Photochemistry of Methoxy-substituted Quinoline and Isoquinoline N-Oxides
Albini, Angelo,Fasani, Elisa,Dacrema, Lucia Maggi
, p. 2738 - 2742 (2007/10/02)
The photochemistry of quinoline 1-oxides and isoquinoline 2-oxides bearing a methoxy-group in the pyridine ring was investigated in protic and aprotic media.The formation of various photoisomers, viz. 3,1-benzoxazepines, 2(1H)-quinolones, N-(2-isocyanobenzyl)formamides, 4(1H)-quinolones, and 3-hydroxyquinolines from the different methoxyquinoline 1-oxides, and 1,3-benzoxazepines and 1(2H)-isoquinolones from the different methoxyisoquinoline 2-oxides, was observed along with deoxygenation and formation of products derived from hydration and decomposition of the primary products.The position of the methoxy-group has an important directing effect on the photoreactions.
