239137-41-8

Basic information

• Product Name: 3-Pyridinamine,4-bromo-N-phenyl-
• Synonyms: 3-Pyridinamine,4-bromo-N-phenyl-
• CAS NO: 239137-41-8
• Molecular Weight: 249.11
• Mol File: 239137-41-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Pyridinamine,4-bromo-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinamine,4-bromo-N-phenyl-(239137-41-8)
• EPA Substance Registry System: 3-Pyridinamine,4-bromo-N-phenyl-(239137-41-8)

Safety Data

• Hazardous Substances Data: 239137-41-8(Hazardous Substances Data)

Upstream product

• 239137-58-7 N-(4-bromo-pyridin-3-yl)-2,2-dimethylpropanamide 
• 70298-88-3 N-(pyridin-3-yl)pivalamide 
• 591-50-4 iodobenzene 
• 239137-39-4 3-amino-4-bromopyridine 

Downstream Products

• 244-63-3 betacarboline 

Relevant articles and documents

Ultrasound assisted one-pot synthesis of 1,2-diaryl azaindoles via Pd/C-Cu catalysis: Identification of potential cytotoxic agents

Ultrasound assisted one-pot and direct access to 1,2-diaryl substituted azaindole derivatives has been achieved via the sequential N-arylation followed by coupling-cyclization under Pd/C-Cu catalysis. The methodology involved initial C[sbnd]N bond forming

One-pot synthesis of 1, 2-disubstituted 4-, 5-, 6-, and 7-azaindoles from amino-o-halopyridines via n-arylation/sonogashira/cyclization reaction

A direct synthesis of several 1, 2-disubstituted 4-, 5-, 6-, and 7-azaindoles from available amino-o-halopyridines is described. This procedure involves a palladium-catalyzed N-arylation followed by a Sonogashira reaction and subsequent cyclization in a one-pot manner, exhibiting a wide scope and compatibility with electron-withdrawing and electron-donating groups. The strategy represents an advancement in azaindole chemistry with a straightforward approach toward 1, 2-disubstituted azaindoles, while avoiding complex N-arylations of hindered 2-substituted azaindoles and difficult purification steps of intermediates.

Novel synthetic strategy of carbolines via palladium-catalyzed amination and arylation reaction

Four parent carbolines and the corresponding 5- or 9-methylsulfonyl derivatives were synthesized by the palladium-catalyzed intramolecular arylation reaction of ortho-bromo-substituted anilinopyridines which were prepared by the palladium-catalyzed amination reaction of iodobenzenes with aminopyridines. Carbazole and its 9-methylsulfonyl derivative were also synthesized by the same method.