2415-33-0

Basic information

• Product Name: 3,3'-Bi-1H-indole,2,2'-diphenyl-
• Synonyms: 3,3'-Biindole,2,2'-diphenyl- (7CI,8CI); NSC 263525
• CAS NO: 2415-33-0
• Molecular Formula: C28H20 N2
• Molecular Weight: 384.48
• Mol File: 2415-33-0.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 3,3'-Bi-1H-indole,2,2'-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-Bi-1H-indole,2,2'-diphenyl-(2415-33-0)
• EPA Substance Registry System: 3,3'-Bi-1H-indole,2,2'-diphenyl-(2415-33-0)

Safety Data

• Hazardous Substances Data: 2415-33-0(Hazardous Substances Data)

Upstream product

• 109-06-8 α-picoline 
• 2196-95-4 2,2'-diphenyl-[3,3']biindolylidene 1,1'-dioxide 
• 108-89-4 picoline 
• 1122-58-3 dmap 
• 108-99-6 3-Methylpyridine 
• 3558-24-5 1-methyl-2-phenyl-1H-indole 
• 1859-39-8 2-phenyl-N-hydroxyindole 
• 98-88-4 benzoyl chloride 
• 104-94-9 4-methoxy-aniline 
• 68-12-2 N,N-dimethyl-formamide 
• 632-22-4 tetramethylurea 
• 127-19-5 N,N-dimethyl acetamide 
• 948-65-2 2-phenyl-indole 
• 96-96-8 4-methoxy-2-nitroaniline 

Downstream Products

• 81235-58-7 3-(1-methyl-2-phenylindol-3-yl)-2-phenylindole 

Relevant articles and documents

Palladium-catalyzed reaction of o-alkynyltrifluoroacetanilides with 1-bromoalkynes. An approach to 2-substituted 3-alkynylindoles and 2-substituted 3-acylindoles

The palladium-catalyzed reaction of o-alkynyltrifluoroacetanilides with 1-bromoalkynes affords free N-H 2-substituted 3-alkynylindoles in satisfactory to high yield. 2-Substituted 3-alkynylindoles revealed useful intermediates for the regioselective synthesis of 2-substituted 3-acylindoles. The latter can be prepared from o-alkynyltrifluoroacetanilides and 1-bromoalkynes via a one-pot cyclization-hydration protocol, omitting the isolation of 2-substituted 3-alkynylindoles.

Carbocatalytic Oxidative Dehydrogenative Couplings of (Hetero)Aryls by Oxidized Multi-Walled Carbon Nanotubes in Liquid Phase

HNO3-oxidized carbon nanotubes catalyze oxidative dehydrogenative (ODH) carbon–carbon bond formation between electron-rich (hetero)aryls with O2 as a terminal oxidant. The recyclable carbocatalytic method provides a convenient and an operationally easy synthetic protocol for accessing various benzofused homodimers, biaryls, triphenylenes, and related benzofused heteroaryls that are highly useful frameworks for material chemistry applications. Carbonyls/quinones are the catalytically active site of the carbocatalyst as indicated by model compounds and titration experiments. Further investigations of the reaction mechanism with a combination of experimental and DFT methods support the competing nature of acid-catalyzed and radical cationic ODHs, and indicate that both mechanisms operate with the current material.

2-Substituted 3-arylindoles through palladium-catalyzed arylative cyclization of 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions

Free NH 2-substituted 3-arylindoles have been prepared usually in good to high yields through the palladium-catalyzed reaction of readily available 2-alkynyltrifluoroacetanilides with arylboronic acids under oxidative conditions. The reaction tolerates a variety of useful functional groups both in the arylboronic acid and in the alkyne, including chloro, formyl, and ester groups.