24214-73-1

Basic information

• Product Name: CYCLOHEXYLHYDRAZINE HYDROCHLORIDE
• Synonyms: CYCLOHEXYLHYDRAZINE HYDROCHLORIDE;1-CYCLOHEXYLHYDRAZINE HYDROCHLORIDE;CyclohexylhydrazineHCl;Hydrazinocyclohexane hydrochloride;Hydrazine, cyclohexyl-,hydrochloride (1:1);Cyclohexylhydrazine hydrochloride 98%;Cyclohexylhydrazine hydrochloride≥ 98%(Titration);Cyclohexylhydrazine monohydrochloride
• CAS NO: 24214-73-1
• Molecular Formula: C₆H₁₄N₂*ClH
• Molecular Weight: 150.65
• Product Categories: Hydrazines;Nitrogen Compounds;Organic Building Blocks
• Mol File: 24214-73-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 110-114 °C(lit.)
• Boiling Point: 210.9 °C at 760 mmHg
• Flash Point: 91.7 °C
• Appearance: White/Crystalline Powder
• Vapor Pressure: 0.188mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Water Solubility: almost transparency
• CAS DataBase Reference: CYCLOHEXYLHYDRAZINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOHEXYLHYDRAZINE HYDROCHLORIDE(24214-73-1)
• EPA Substance Registry System: CYCLOHEXYLHYDRAZINE HYDROCHLORIDE(24214-73-1)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3263 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: Ⅱ
• Hazardous Substances Data: 24214-73-1(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow powder,crystals or

InChI:InChI=1/C6H14N2.ClH/c7-8-6-4-2-1-3-5-6;/h6,8H,1-5,7H2;1H

Upstream product

• 60295-21-8 N'-cyclohexyl-hydrazine carboxylic acid tert-butyl ester 
• 60295-11-6 tert-butyl 2-cyclohexylidenehydrazine-1-carboxylate 
• 108-94-1 cyclohexanone 
• 931-51-1 cyclohexylmagnesiumchloride 

Downstream Products

• 346684-16-0 methyl 1-cyclohexyl-5-(4-methylthiophenyl)pyrazol-3-carboxylate 
• 32137-21-6 cyclohexylhydrazone of cyclohexanone 
• 52867-47-7 2-cyclohexyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester 
• 21254-04-6 5-amino-1-cyclohexyl-1H-pyrazol-4-carbonitrile 
• 374641-79-9 5-(adamantan-1-yloxymethyl)-2-cyclohexyl-2H-pyrazol-3-ol 
• 21253-62-3 ethyl 5-amino-1-cyclohexyl-1H-pyrazole-4-carboxylate 
• 934417-06-8 C₁₈H₂₈N₂O₂ 
• 1355228-94-2 2-oxopropanal cyclohexyl-hydrazone 
• 743434-23-3 C₂₃H₂₂BrF₃N₂O 
• 743434-22-2 C₂₃H₂₂BrF₃N₂O 
• 1203703-98-3 1-cyclohexyl-4-phenylpyrazole 
• 1257542-13-4 C₁₃H₂₂N₄O 

Relevant articles and documents

Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis

We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.

PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION

Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis.

INHIBITORS OF BRUTON'S TYROSINE KINASE

The invention provides novel poly-substituted 5-membered heterocyclic compounds represented by Formula (IV), or a pharmaceutically acceptable salt, solvate, metabolites, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as selective irreversible bruton's tyrosine kinase (Btk) inhibitors and is further useful to treat inflammatory, auto immune diseases associated with aberrant B-cell proliferation such as RA (rheumatoid arthritis) and cancers. This invention also provided the preparation of a medicament using of Formula (IV), and methods of preventing or treating diseases associated with excessive Btk activity in mammals, especially humans. Formula (IV)