24456-96-0

Basic information

• Product Name: 2-tert-butyl-5-methylbenzo-1,4-quinone
• Synonyms: 2-tert-butyl-5-methylbenzo-1,4-quinone
• CAS NO: 24456-96-0
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• Mol File: 24456-96-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-tert-butyl-5-methylbenzo-1,4-quinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butyl-5-methylbenzo-1,4-quinone(24456-96-0)
• EPA Substance Registry System: 2-tert-butyl-5-methylbenzo-1,4-quinone(24456-96-0)

Safety Data

• Hazardous Substances Data: 24456-96-0(Hazardous Substances Data)

Usage

General Description

2-tert-butyl-5-methylbenzo-1,4-quinone is a chemical compound with a molecular formula of C16H22O2. It is a yellow crystalline solid that is insoluble in water and sparingly soluble in most organic solvents. The compound is commonly used as a co-catalyst in various oxidation reactions and is known for its ability to act as an efficient electron transfer mediator. It is also utilized in the synthesis of pharmaceuticals and as a reagent in organic chemistry. Additionally, 2-tert-butyl-5-methylbenzo-1,4-quinone possesses antioxidant properties, making it potentially valuable in the food and cosmetic industries for its ability to inhibit the oxidation of fats and oils. However, it should be handled with caution as it is a hazardous chemical with potential health and environmental risks.

Upstream product

• 497-39-2 4,6-di-tert-butyl-m-cresol 
• 119711-73-8 4-(tert-butylperoxy)-4-methyl-2,5-cyclohexadien-1-one 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 85336-17-0 5-tert-butyl-2-methylaniline 
• 62559-08-4 4-tert-butyl-2-nitrotoluene 
• 88-60-8 2-tert-Butyl-5-methylphenol 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 7664-93-9 sulfuric acid 
• 5781-02-2 5-(tert-butyl)-2-methylphenol 
• 88-40-4 2-tert-butyl-5-methylanisole 
• 71-43-2 benzene 
• 22236-19-7 pentafluorobenzoyl peroxide 
• 92101-95-6 2-methyl-5-tert-butyl-1,4-dimethoxybenzene 

Downstream Products

• 2349-76-0 2-methyl-5-tert-butylhydroquinone 

Relevant articles and documents

Organophotocatalytic Aerobic Oxygenation of Phenols in a Visible-Light Continuous-Flow Photoreactor

A mild photocatalytic phenol oxygenation enabled by a continuous-flow photoreactor using visible light and pressurized air is described herein. Products for wide-ranging applications, including the synthesis of vitamins, were obtained in high yields by precisely controlling principal process parameters. The reactor design permits low organophotocatalyst loadings to generate singlet oxygen. It is anticipated that the efficient aerobic phenol oxygenation to benzoquinones and p-quinols contributes to sustainable synthesis.

Synthesis of 2-substituted quinones, vitamin K3, and vitamin K1 from p-cresol. BF3·OEt2-catalyzed methyl migration of 4-tert-butyldioxycyclohexadienones

BF3·OEt2-catalyzed methyl group migration of 4-methyl-4-tert-butyldioxycyclohexadienone, which is obtained by ruthenium-catalyzed oxidation of p-cresol with tert-butyl hydroperoxide, in hexafluoro-2-propanol/toluene gave toluquinone efficiently. The reaction can be applied to the regio-selective short-step syntheses of vitamin K3 and vitamin K1 from p-cresol.

Convenient oxidation of alkylated phenols and methoxytoluenes to antifungal 1,4-benzoquinones with hydrogen peroxide (H2O2)/methyltrioxorhenium (CH3ReO3) catalytic system in neutral ionic liquid

Alkylated phenol and methoxytoluene derivatives were catalytically and selectively oxidized to the corresponding 1,4-benzoquinones in good conversions and yields. Reactions were performed with hydrogen peroxide (H2O2)/methyltrioxorhenium (CH3ReO3) in 1-butyl-3-methylimidazolium tetrafluoroborate [bmim]BF4, a neutral ionic liquid. Compounds were tested in vitro for their antifungal activity against the growth of several widespread soil fungi. Some of them were proved to be potent inhibitors of Fusarium sp. than ketoconazole, a commercially available and expensive antifungal agent.