245-37-4

Basic information

• Product Name: 4,5-Diazafluorene
• Synonyms: 4,5-Diaza-9H-fluorene;4,5-Diazafluorene;5H-Cyclopenta[2,1-b:3,4-b']dipyridine
• CAS NO: 245-37-4
• Molecular Formula: C₁₁H₈N₂
• Molecular Weight: 168.19
• Mol File: 245-37-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 172 °C
• Boiling Point: 358.0±22.0 °C(Predicted)
• Appearance: /
• Density: 1.247±0.06 g/cm3(Predicted)
• PKA: 4.27±0.20(Predicted)
• CAS DataBase Reference: 4,5-Diazafluorene(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Diazafluorene(245-37-4)
• EPA Substance Registry System: 4,5-Diazafluorene(245-37-4)

Safety Data

• Hazardous Substances Data: 245-37-4(Hazardous Substances Data)

Upstream product

• 7291-22-7 perdeuteriopyridine 
• 1415222-47-7 (pentamethylcyclopentadienyl)₂Yb(4,5-diazafluorene) 
• 90299-47-1 5,5'-hydrazine-1,2-diylidene-bis(5H-pyrido[3',2':4,5]cyclopenta[1,2-b]pyridine) 
• 90299-45-9 4,5-diazafluorenone-9-hydrazone 
• 50890-67-0 4,5-Diazafluoren-9-one 

Related news

A ruthenium(II) bipyridine complex containing a 4,5-Diazafluorene (cas 245-37-4) moiety: Synthesis, characterization and its applications in transfer hydrogenation of ketones and dye sensitized solar cells09/28/2019

The ruthenium(II) complex [Ru(bpy) 2 L](PF 6 ) 2 , where bpy is 2,2′-bipyridine and L is 1,5-dihydro-2-H-cyclopenta[1,2-b:5,4-b′]dipyridine-2-one, was synthesized from the reaction of cis-Ru(bpy) 2 Cl 2 ·2H 2 O with L, and isolated as the hexafl...detailed

Relevant articles and documents

Synthesis of 9,9-dialkyl-4,5-diazafluorene derivatives and their structure-activity relationships toward human carcinoma cell lines

A homologous set of 9,9-dialkyl-4,5-diazafluorene compounds were prepared by alkylation of 4,5-diazafluorene with the appropriate alkyl bromide and under basic conditions. The structures of these simple organic compounds were confirmed by spectroscopic techniques (FTIR, NMR, and FABMS). Their biological effects toward a panel of human carcinoma cells, including Hep3B hepatocellular carcinoma, MDAMB-231 breast carcinoma, and SKHep-1 hepatoma cells, were investigated; a structure-activity correlation was established with respect to the length of the alkyl chain and the fluorene ring structure. The relationship between the mean potency [log(1/IC50)] and alkyl chain length was systematically studied. The results show that compounds with butyl, hexyl, and octyl chains exhibit good growth inhibitory effects toward these three human carcinoma cell lines, and the 9,9-dihexyl-4,5-diazafluorene further exhibits antitumor activity in athymic nude mice Hep3B xenograft models. For the structurally related dialkylfluorenes that lack the diaza functionality, in vitro cytotoxicity was not observed at clinically relevant concentrations.

SELECTIVE PERTURBATION OF LIGAND FIELD EXCITED STATES IN POLYPYRIDINE RUTHENIUM(II) COMPLEXES.

A new bipyridine-type ligand which allows the selective perturbation of ligand field (LF) excited-state energies is introduced. Any metal-to-ligand charge-transfer (MLCT) excited states occur at nearly the same energy as in the bipyridine complex. The syntheses of the corresponding ruthenium(II) complexes and their photophysical properties are reported. The results clearly support a current model for the excited-state behavior of polypyridine complexes in which the lowest MLCT decays by thermal population of a higher lying LF state. This method of selective LF-state perturbation nicely complements the perturbation of MLCT states achieved by modification of the ligand's reduction potential.

4,5-diazafluorene derivative, preparation method and applications thereof

The invention relates to a 4,5-diazafluorene derivative, a preparation method and applications thereof, wherein a 1,10-phenanthroline monohydrate and potassium permanganate are subjected to an oxidizing reaction to obtain a 4,5-diazafluoren-9-one intermed

NOVEL COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

In the present invention, disclosed are a compound of an organic electroluminescent device denoted by structural formula 1 and an organic electroluminescent device including the same. In the present invention, provided are a compound of an organic electroluminescent device which has outstanding electrical stability and electron and hole transport performance and exhibits high triplet energy level, thereby being used as hosts, hole transport materials and electron transport materials to increase light emitting efficiency of phosphorescent luminescent materials, and an organic electroluminescent device.