247132-60-1

Basic information

• Product Name: 4-[4-[N-Benzyloxycarbonyl-N-(2-tert-butoxycarbonylmethylamino-5-cyanophenyl)carbamoylmethylamino]phenoxy]piperidine-1-carboxylic Acid tert-Butyl Ester
• Synonyms: 4-[4-[N-Benzyloxycarbonyl-N-(2-tert-butoxycarbonylmethylamino-5-cyanophenyl)carbamoylmethylamino]phenoxy]piperidine-1-carboxylic Acid tert-Butyl Ester
• CAS NO: 247132-60-1
• Molecular Weight: 713.831
• Mol File: 247132-60-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[4-[N-Benzyloxycarbonyl-N-(2-tert-butoxycarbonylmethylamino-5-cyanophenyl)carbamoylmethylamino]phenoxy]piperidine-1-carboxylic Acid tert-Butyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-[N-Benzyloxycarbonyl-N-(2-tert-butoxycarbonylmethylamino-5-cyanophenyl)carbamoylmethylamino]phenoxy]piperidine-1-carboxylic Acid tert-Butyl Ester(247132-60-1)
• EPA Substance Registry System: 4-[4-[N-Benzyloxycarbonyl-N-(2-tert-butoxycarbonylmethylamino-5-cyanophenyl)carbamoylmethylamino]phenoxy]piperidine-1-carboxylic Acid tert-Butyl Ester(247132-60-1)

Safety Data

• Hazardous Substances Data: 247132-60-1(Hazardous Substances Data)

Upstream product

• 6456-74-2 Glycine tert-butyl ester 
• 16357-59-8 N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline 
• 247132-59-8 N-(2-amino-4-cyanophenyl)glycine tert-butyl ester 
• 247132-57-6 N-[4-(1-tert-butoxycarbonylpiperidin-4-yloxy)phenyl]-N-benzyloxycarbonyl-aminoacetic acid 
• 247132-56-5 4-[4-(N-benzyloxycarbonyl-N-ethoxycarbonyl-methylamino)phenoxy]piperidine-1-carboxylic acid tert-butyl ester 
• 247132-58-7 N-(4-Cyano-2-nitrophenyl)glycine tert-butyl ester 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 
• 138227-63-1 tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate 
• 939-80-0 4-chloro-3-nitrobenzonitrile 

Downstream Products

• 247133-56-8 N-[4-Cyano-2-[4-(1-tert-butoxycarbonylpiperidin-4-yloxy)phenoxyacetamido]-phenyl]glycine tert-Butyl Ester 
• 247131-64-2 N-(4-cyano-2-phenoxyacetamidophenyl)glycine tert-butyl ester 
• 247132-61-2 2-[N-Benzyloxycarbonyl-N-[4-(1-tert-butoxycarbonylpiperidin-4-yloxy)phenyl]-aminomethyl]-5-cyanobenzimidazole-1-acetic Acid 
• 247133-81-9 2-[N-[4-(1-tert-butoxycarbonylpiperidin-4-yloxy)phenyl]-N-(4-methoxycarbonylbenzoyl)aminomethyl]-1-(cyclohexylcarbamoylmethyl)-benzimidazole-5-carboxamidine 
• 247132-64-5 (S)-2-[N-[4-(1-tert-Butoxycarbonylpiperidin-4-yloxy)phenyl]-N-(4-methoxycarbonylbenzoyl)aminomethyl]-1-(1-phenylethylcarbamoylmethyl)-benzimidazole-5-carboxamidine 
• 247133-80-8 2-[N-[4-(1-tert-Butoxycarbonylpiperidin-4-yloxy)phenyl]-N-(4-methoxycarbonyl-benzoyl)aminomethyl]-1-(cyclohexylcarbamoylmethyl)-5-cyanobenzimidazole 

Relevant articles and documents

Structure-activity relationships of potent and selective factor Xa inhibitors: benzimidazole derivatives with the side chain oriented to the prime site of factor Xa.

A series of benzimidazole derivatives with the side chain on the nitrogen atom oriented to the prime site of factor Xa (FXa) were designed and synthesized. Compounds with substituted aminocarbonylmethyl groups as the side chain showed potent FXa inhibitor