2491-91-0

Basic information

• Product Name: 2,5-di-(4-methylphenyl)-1,3-4-oxadiazole
• Synonyms: 2,5-di-(4-methylphenyl)-1,3-4-oxadiazole;2,5-di(p-tolyl)-1,3,4-oxadiazole
• CAS NO: 2491-91-0
• Molecular Formula: C₁₆H₁₄N₂O
• Molecular Weight: 250.30
• Mol File: 2491-91-0.mol
• Article Data: 38

Chemical Properties

• Boiling Point: 399 °C at 760 mmHg
• Flash Point: 189.3 °C
• Appearance: /
• Density: 1.128 g/cm³
• Vapor Pressure: 3.26E-06mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 2,5-di-(4-methylphenyl)-1,3-4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-di-(4-methylphenyl)-1,3-4-oxadiazole(2491-91-0)
• EPA Substance Registry System: 2,5-di-(4-methylphenyl)-1,3-4-oxadiazole(2491-91-0)

Safety Data

• Hazardous Substances Data: 2491-91-0(Hazardous Substances Data)

Usage

Description

2,5-di-(4-methylphenyl)-1,3,4-oxadiazole is a chemical compound belonging to the 1,3,4-oxadiazole class, characterized by the molecular formula C16H14N2O. It is a crystalline solid known for its diverse biological and pharmacological activities. 2,5-di-(4-methylphenyl)-1,3-4-oxadiazole is highly valued in the field of organic synthesis for its unique structure and properties, which contribute to the development of advanced materials.

Uses

Used in Organic Synthesis:
2,5-di-(4-methylphenyl)-1,3,4-oxadiazole is used as a building block in organic synthesis for the preparation of various functional materials. Its unique structure and properties make it a valuable component in creating advanced materials.
Used in Liquid Crystals Industry:
In the liquid crystals industry, 2,5-di-(4-methylphenyl)-1,3,4-oxadiazole is used as a key component for developing liquid crystal materials. Its incorporation enhances the performance characteristics of liquid crystals, making them suitable for various applications such as displays and sensors.
Used in Polymer Industry:
2,5-di-(4-methylphenyl)-1,3,4-oxadiazole is used as a monomer in the polymer industry for synthesizing polymers with specific properties. Its unique structure contributes to the development of polymers with tailored characteristics for use in different industries.
Used in Organic Semiconductors Industry:
In the organic semiconductors industry, 2,5-di-(4-methylphenyl)-1,3,4-oxadiazole is used as a constituent in the design and synthesis of organic semiconductors. Its properties are leveraged to create semiconductor materials with improved performance for applications in electronic devices and optoelectronics.

InChI:InChI=1/C16H14N2O/c1-11-3-7-13(8-4-11)15-17-18-16(19-15)14-9-5-12(2)6-10-14/h3-10H,1-2H3

Upstream product

• 1530-73-0 4-methyl-N'-(4-methylbenzoyl)benzohydrazide 
• 874-60-2 4-methyl-benzoyl chloride 
• 3619-22-5 p-toluic hydrazide 
• 115540-63-1 N'-(4-methylbenzylidene)-4-methylbenzohydrazide 
• 100-47-0 benzonitrile 
• 99-94-5 p-Toluic acid 
• 38663-38-6 2',2'-dibenzyl-4-methylbenzohydrazide 
• 93-97-0 benzoic acid anhydride 
• 155164-67-3 4,5-Dichloro-2-(4-methyl-benzoyl)-2H-pyridazin-3-one 
• 139030-29-8 (1E,2E)-1,2-bis(4-methylbenzylidene)hydrazine 
• 100-44-7 benzyl chloride 
• 24994-04-5 5-(p-tolyl)-1H-tetrazole 
• 104-87-0 4-methyl-benzaldehyde 
• 827-58-7 2-p-tolyl-1,3,4-oxadiazole 

Downstream Products

• 16157-40-7 2,5-bis-[4-(trans-2-thiophen-2-yl-vinyl)-phenyl]-[1,3,4]oxadiazole 
• 16157-37-2 2,5-bis-[4-(trans-2-biphenyl-4-yl-vinyl)-phenyl]-[1,3,4]oxadiazole 
• 16157-35-0 2,5-bis-[4-(4-isopropyl-trans-styryl)-phenyl]-[1,3,4]oxadiazole 
• 16157-33-8 2,5-bis(4-styrylphenyl)-1,3,4-oxadiazole 
• 16157-34-9 2,5-bis(4-(4-chlorostyryl)phenyl)-1,3,4-oxadiazole 
• 61528-64-1 2,5-di-p-tolyl-(5ar,10ac)-10,10a-dihydro-5aH-indeno[1,2-f][1,3,4]oxadiazepine 
• 787-84-8 N'-benzoylbenzohydrazide 
• 75029-44-6 1,3-dimethyl-5-benzoylpyrimidine-2,4(1H,3H)-dione 
• 75029-41-3 1,3-Dimethyl-5-(4-methylbenzoyl)uracil-(4-methylbenzoyl)hydrazon 
• 65-85-0 benzoic acid 
• 58370-39-1 2,5-bis[4-(bromomethyl)phenyl]-1,3,4-oxadia-zole 
• 500615-67-8 2,5-bis-(4-methyl-3-nitro-phenyl)-[1,3,4]oxadiazole 
• 58370-38-0 diethyl 4-(5-(4-(diethoxyphosphino)methylphenyl)-1,3,4-oxadiazol-2-yl)-benzyl-phosphonate 
• 67603-32-1 C₁₆H₁₆N₄O 

Relevant articles and documents

New heterocycle-based organic molecule with two-photon induced blue fluorescent emission

A new heterocycle-based quadrupolar molecule containing 2,5-diphenyl-1,3,4-oxadiazole as the n -centre and two carbazoles as end units has been synthesized. It exhibits two-photon induced blue emission, and its two-photon absorption cross section in the femtosecond region is measured to be 239 × 10-50 cm4 s photon-1 at a wavelength of 788 nm. CSIRO 2006.

Multipolar symmetric and asymmetric N–heterocyclic compounds with efficient two?photon absorption

A series of novel multipolar symmetric and asymmetric N–heterocyclic compounds with different configurations were designed and synthesized. Their structures were characterized by Fourier transform infrared spectroscopy, hydrogen?1 nuclear magnetic resonan

Palladium-catalyzed direct C2-arylation of azoles with aromatic triazenes

A highly efficient palladium-catalyzed arylation of azoles at the C2-position using 1-aryltriazenes as aryl reagents was developed. Azoles including oxazoles, thiazoles, imidazoles, 1,3,4-oxadiazoles, and oxazolines could react with 1-aryltriazenes smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.

Synthesis method of 2,5-disubstituted-1,3,4-oxadiazole

The invention discloses a synthesis method of a drug intermediate, namely, 2,5-disubstituted-1,3,4-oxadiazole. 2,5-disubstituted-1,3,4-oxadiazole is synthesized with a one-pot method under the photocatalytic action with simple hydrazide compounds as raw materials. 2,5-disubstituted-1,3,4-oxadiazole can be produced through a reaction at the room temperature with a common halogen lamp as a light source, eosinY as a catalyst, potassium carbonate as an additive and ethanol as a solvent. The method has the characteristics that the raw material source is simple, the reaction condition is mild and the like.