24929-02-0Relevant articles and documents
Tuong,Mida
, p. 1763 (1970)
Combinatorial synthesis of anilinoanthraquinone derivatives and evaluation as non-nucleotide-derived P2Y2 receptor antagonists
Weyler, Stefanie,Baqi, Younis,Hillmann, Petra,Kaulich, Marko,Hunder, Andrea M.,Mueller, Ingrid A.,Mueller, Christa E.
, p. 223 - 227 (2008/09/19)
A library of anilinoanthraquinone derivatives was synthesized by parallel Ullmann coupling reaction of bromaminic acid with aniline derivatives in solution using a compact parallel synthesizer. The products were purified by HPLC and evaluated as antagonists at mouse and human P2Y2 receptors. 4-Phenylamino-substituted 1-amino-2-sulfoanthraquinones, for example, 1-amino-4-(2-methoxyphenyl)-2-sulfoanthraquinone (PSB-716), were potent P2Y2 antagonists with IC50 values in the low micromolar range.
REACTION OF ISOMERIC 1,4-AMINOHYDROXYANTHRAQUINONE-2-SULFONIC ACIDS WITH AMMONIA
Kwong, Hang Ir,Shishkina, E. Yu.,Vorozhtsov, G. N.
, p. 604 - 605 (2007/10/02)
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