25110-46-7

Basic information

• Product Name: 2-(4-Methoxyphenyl)-1H-perimidine
• Synonyms: 2-(4-Methoxyphenyl)-1H-perimidine
• CAS NO: 25110-46-7
• Molecular Formula: C₁₈H₁₄N₂O
• Molecular Weight: 274.32
• Mol File: 25110-46-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Methoxyphenyl)-1H-perimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)-1H-perimidine(25110-46-7)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)-1H-perimidine(25110-46-7)

Safety Data

• Hazardous Substances Data: 25110-46-7(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound

Core structure

Perimidine ring system

Substituent

Methoxyphenyl group

Position of substituent

2-position

Use in research

Building block for new drugs and biologically active molecules

Interest to professionals

Medicinal chemists and pharmacologists

Focus of study

Structure-activity relationships of biologically active compounds

Potential applications

Organic synthesis and materials science

Unique features

Structure and reactivity

Upstream product

• 19564-09-1 2-(4-methoxyphenyl)-2,3-dihydro-1H-1H-2,3-dihydro1H-2,3-dihydroperimidine 
• 100-07-2 4-methoxy-benzoyl chloride 
• 602-38-0 1,8-dinitronaphthalene 
• 123-11-5 4-methoxy-benzaldehyde 
• 15795-54-7 5-(4-methoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione 
• 479-27-6 naphthalene-1,8-diamine 

Downstream Products

• 59283-21-5 2-(4-methoxy-phenyl)-1-methyl-1H-perimidine 

Relevant articles and documents

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Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors

For the development of novel anticancer agents, we designed and synthesized a total of 37 perimidine o-quinone derivatives containing the o-quinone group at the A or B ring and different substituents (alkyl groups, aryl groups or heterocycles) at the C ri

Synthesis of 2-aryl-1H-benzimidazoles and 2-aryl-1H-perimidines using arylidene Meldrum’s acid as a source of the aryl group and oxidant

Arylidene Meldrum’s acid is employed as a source of the aryl group and oxidant for the synthesis of 2-aryl-1H–benzimidazoles by a condensation reaction with 1,2-phenylenediamine in refluxing ethanol with good to high yields. Arylidene Meldrum’s acids were