253342-48-2

Basic information

• Product Name: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)toluene
• Synonyms: 2-(3-TOLYL)-4,4,6-TRIMETHYL-1,3,2-DIOXABORINATE;3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)TOLUENE;3-TOLYLBORONIC ACID, HEXYLENE GLYCOL CYCLIC ESTER;3-METHYLPHENYLBORONIC ACID, PINACOL ESTER;2-dioxaborolan-2-yl)toluene;3-Methylbenzeneboronic acid, pinacol ester;4,4,5,5-Tetramethyl-2-m-tolyl-1,3,2-dioxaborolane;4,4,5,5-tetraMethyl-2-(3-Methylphenyl)-1,3,2-dioxaborolane
• CAS NO: 253342-48-2
• Molecular Formula: C₁₃H₁₉BO₂
• Molecular Weight: 218.1
• Mol File: 253342-48-2.mol
• Article Data: 133

Chemical Properties

• Melting Point: 34.0 to 38.0 °C
• Boiling Point: 307.2 °C at 760 mmHg
• Flash Point: 139.6 °C
• Appearance: /
• Density: 0.98 g/cm³
• Vapor Pressure: 0.00134mmHg at 25°C
• Refractive Index: 1.491
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)toluene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)toluene(253342-48-2)
• EPA Substance Registry System: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)toluene(253342-48-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 253342-48-2(Hazardous Substances Data)

Usage

Uses

suzuki reaction

InChI:InChI=1/C13H19BO2/c1-10-7-6-8-11(9-10)14-15-12(2,3)13(4,5)16-14/h6-9H,1-5H3

Upstream product

• 108-88-3 toluene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 625-95-6 3-Iodotoluene 
• 591-17-3 meta-bromotoluene 
• 73183-34-3 bis(pinacol)diborane 
• 745783-97-5 triethyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 17933-03-8 m-tolylboronic acid 
• 28987-79-3 m-tolylmagnesium bromide 
• 931-88-4 1,2-cyclooctene 
• 108-41-8 1-chloro-3-methylbenzene 
• 121-72-2 N,N-dimethyl-m-toluidine 
• 502630-89-9 2-(3-chloro-5-methylphenyl)-4,4,5,5-tetra methyl-1,3,2-dioxaborolane 
• 637-04-7 (3-methylphenyl)hydrazine hydrochloride 

Downstream Products

• 17933-03-8 m-tolylboronic acid 
• 1256781-59-5 2-(2-bromo-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 76650-29-8 4-acetyl-3'-methylbiphenyl 
• 643-65-2 3-methyl benzophenone 
• 108-88-3 toluene 
• 36821-15-5 2-(3-methylphenyl)naphthalene 
• 851775-42-3 2-(3-methylphenyl)-5-methylpyridine 
• 40395-27-5 N-benzyl-N,N'-diphenylhydrazine 
• 401-79-6 1-methyl-3-trifluoromethyl-benzene 
• 214360-46-0 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 
• 1333419-38-7 (Z)-methyl 3-(2-oxopyrrolidin-1-yl)-3-(m-tolyl)acrylate 
• 195062-57-8 p-tolylboronic pinacol ester 
• 195062-59-0 2-methylphenylboronic acid pinacol ester 
• 214360-74-4 2-(3-(bromomethyl)phenyl)-4,4,5,5,-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Cu-mediated: vs. Cu-free selective borylation of aryl alkyl sulfones

A Cu-catalysed borylation of aryl alkyl sulfones was developed for the high yield synthesis of versatile arylboronic esters using a readily prepared NHC-Cu catalyst. In addition, the selective cleavage of either alkyl(C)-sulfonyl or aryl(C)-sulfonyl bonds

Photochemical and electrochemical C-N borylation of arylhydrazines

The C-N borylation of arylhydrazine hydrochlorides with bis(pinacolato)diboron was achieved under photochemical and electrochemical conditions, respectively. This novel and scalable transformation provides two efficient and mild transition-metal-free synt

Unreactive C-N Bond Activation of Anilines via Photoinduced Aerobic Borylation

Unreactive C-N bond activation of anilines was achieved by photoinduced aerobic borylation. A diverse range of tertiary and secondary anilines were converted to aryl boronate esters in moderate to good yields with wide functional group tolerance under simple and ambient photochemical conditions. This transformation achieved the direct and facile C-N bond activation of unreactive anilines, providing a convenient and practical route transforming widely available anilines into useful aryl boronate esters.