2555-10-4Relevant articles and documents
Corresponding amine nitrile and method of manufacturing thereof
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Paragraph 0236, (2017/10/22)
The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.
PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS
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Page/Page column 93, (2008/06/13)
Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas (1 or 2), as described herein. The compounds of Formulas (1 and 2) are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.
Reduction d'azides par la triphenylphosphine en presence d'eau : une methode generale et chimioselective d'acces aux amines primaires
Knouzi, Noureddine,Vaultier, Michel,Carrie, Robert
, p. 815 - 819 (2007/10/02)
The reaction of azides with one equivalent of triphenylphosphine in the presence of a slight excess of water in THF leads quantitatively to the corresponding primary amines.This transformation is chemoselective.