2563-84-0Relevant articles and documents
Pyrolysis of perhydro[1,2-c][1,3]oxazines: A green method of synthesizing 2,3-dehydropiperidine enamines
Cook, A. Gilbert,Schering, Christine A.,Campbell, Pauline A.,Hayes, Samantha S.
, p. 5451 - 5454 (2005)
Heat pyrolysis of the oxazines formed from 2-piperidineethanol produced 2,3-dehydropiperidine enamines. The same results were observed when these oxazines were irradiated with microwaves. Various 2-substituted perhydrooxazines were synthesized by allowing 2-piperidineethanol or 2-piperidinemethanol to react with aldehydes or ketones.
Novel application of electrooxidative method for the cyclization of N-benzyl-2-(hydroxymethyl)-and N-benzyl-2-(2-hydroxyethyl)piperidines
Okimoto, Mitsuhiro,Yoshida, Takashi,Hoshi, Masayuki,Ohashi, Kousuke
, p. 2471 - 2478 (2011/04/26)
Several novel 1,3-oxazinane and oxazolidine derivatives were obtained from the corresponding N-benzyl-2-(2-hydroxyethyl)-and N-benzyl-2-(hydroxymethyl) piperidines via electrochemical oxidation. The reactions were carried out in methanol under basic conditions. The yields of the cyclic products were significantly improved using catalytic amounts of iodide ions, which presumably act as effective electron carriers in the two-electron oxidation process. The Japan Institute of Heterocyclic Chemistry.
