25753-22-4 Usage
Description
2,4,6-Tris(trifluoromethyl)aniline is an organic compound characterized by the presence of three trifluoromethyl groups attached to the aniline molecule. 2,4,6-TRIS(TRIFLUOROMETHYL)ANILINE is known for its unique properties, such as increased stability and reactivity, which make it a valuable tool in various applications.
Uses
Used in Medical Chemistry:
2,4,6-Tris(trifluoromethyl)aniline is used as a valuable tool in medical chemistry due to its fluorinated substituents. These fluorinated groups enhance the compound's stability and reactivity, making it suitable for various pharmaceutical applications.
Used in the Preparation of Azo Dyes:
2,4,6-Tris(trifluoromethyl)aniline is also used in the preparation of azo dyes containing fluorine. The presence of fluorine in these dyes provides improved properties, such as increased color strength and resistance to fading, making them suitable for various industrial applications, including textiles, plastics, and printing inks.
Check Digit Verification of cas no
The CAS Registry Mumber 25753-22-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,5 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 25753-22:
(7*2)+(6*5)+(5*7)+(4*5)+(3*3)+(2*2)+(1*2)=114
114 % 10 = 4
So 25753-22-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H4F9N/c10-7(11,12)3-1-4(8(13,14)15)6(19)5(2-3)9(16,17)18/h1-2H,19H2
25753-22-4Relevant articles and documents
An expedient synthesis of 2,4,6-tris(trifluoromethyl)aniline
Edelbach, Brian L.,Pharoah, Blaze M.,Bellows, Sarina M.,Thayer, Peter R.,Fennie, Charles N.,Cowley, Ryan E.,Holland, Patrick L.
, p. 3595 - 3597 (2013/02/22)
A simple two-step synthetic route leads to 2,4,6-tris(trifluoromethyl) aniline. It proceeds through deprotonation and iodination of 1,3,5-tris(trifluoromethyl)benzene, followed by copper-catalyzed amination. Georg Thieme Verlag KG Stuttgart - New York.
Preparation and reactions of 2,4,6-tris(trifluoromethyl)phenylamine
Ahlemann, Jens-T,Roesky, Herbert W.,Noltemeyer, Mathias,Schmidt, Hans-G.,Markovsky, Leonid N.,Shermolovich, Yuri G.
, p. 87 - 90 (2007/10/03)
Starting from RfH (1) [Rf = 1,3,5-tris(trifluoromethyl)phenyl] RfNH2 (6) is obtained in a four-step synthesis. The amine 6 reacts with chlorotrimethylsilane in the presence of DBU (1,8-diazabicyclo(5,4,0)undec-7
