2593-15-9 Usage
Description
Etridiazole, also known as 5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole, is a contact fungicide that was first described in 1969. It is a member of the class of thiadiazoles and is characterized by its trichloromethyl and ethoxy groups. Etridiazole is formulated as a wettable powder (Terrazole) and is used for the control of soilborne diseases caused by Pythium and Phytophthora.
Used in Agricultural Industry:
Etridiazole is used as a fungicide for seed treatment on various crops such as barley, beans, corn, cotton, peanuts, peas, sorghum, soybeans, safflower, and wheat. It is also used for in-furrow application at planting on cotton, on ornamental plants and shrubs by horticultural nurseries, on non-bearing citrus and non-bearing coffee, and for golf course fairways, tees, and greens. Some states hold Special Local Need registrations for its use on tobacco transplants.
Used in Ornamentals Industry:
Etridiazole is used as a contact fungicide with protective and curative action to control Phytophthora and Pythium spp. in ornamentals. It is formulated as a WP (Terrazole) and may be used in a preventive program for control of Pythium blight in turf and of damping-off in ornamentals.
Used in Cannabis Testing Industry:
Etridiazole is used as a component of pesticide mixes in cannabis testing kits, with the specific product code P698235. It can be incorporated into the soil or compost to control Phytophthora spp. and Pythium spp., ensuring the quality and safety of cannabis products.
Used in Cotton Industry:
Etridiazole is used in cotton for in-furrow application at planting to control seedling diseases such as Rhizoctonia, Pythium, and Fusarium. It is also formulated in mixture with pentachloronitrobenzene (quintozene) as Terraclor Super X, which is applied in-furrow to cotton for effective control of these diseases. Application rates in cotton are equivalent to 1 to 1.5 and 0.26 to 0.39 kg ai ha?1 for PCNB and etridiazole, respectively.
Trade name
AATERRA?; BANROT? (With
Thiophanate-methyl); DWELL?[C]; ETHAZOLE?;
4-WAY?; KOBAN?; MF-344?; OLIN MATHIESON?
2,424; OM? 2424; PANSOIL?; TERRACHLOR-SUPER X? (with Pentachloronitrobenzene); TERRACLOR SUPER
X? (with Pentachloronitrobenzene); TERRACOAT?;
TERRAFLO?; TERRAMASTER?; TRUBAN?
Metabolic pathway
The main metabolic pathways of etridiazole in mammals are dechlorination
of the 3-trichloromethyl moiety followed by oxidation yielding
the carboxylic acid derivative or glutathione-mediated dechlorination.
Catabolism of the glutathione conjugate via the mercapturic acid pathway
affords the cysteine conjugate that is in turn N-acetylated to give the
mercapturic acid.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. Military driver shall be given full and
complete information regarding shipment and conditions in
case of emergency. AR 50-6 deals specifically with the
shipment of chemical agents. Shipments of agent will be
escorted in accordance with AR 740-32.
Degradation
The DT50 for hydrolysis of etridiazole is 103 days (25 °C, pH 6). The compound
was hardly decomposed at 20 °C by sunlight over 7 days (PM).
The rate of hydrolysis of etridiazole increased with pH and temperature
and the only product was 3-carboxy-5-ethoxy-1,2,4-thiadiazole (2) (EPA,
1980).
Toxicity evaluation
Etridiazole has low acute toxicity toward mammals
(rat: oral LD50 1,100 mg/kg; rabbit: dermal LD50 >
5,000 mg/kg; rat: inhalation LC50 (4 h) 5.7 mg/L), and
birds (mallard duck: LC50 1,650 mg/kg; bobwhite quail:
LC50 > 5,000 mg/kg). It is also nonteratogenic. However,
chronic administration to rats was associated with an
increased incidence of thyroid follicular cell tumors, and
etridiazole (Terrazole) is included by the EPA in its list of
Group B2 carcinogens.The only noteworthy ecotoxicological effect concerns
the aquatic toxicity of the combination product, Terraclor
Super X, which is highly toxic towards both fish and
Daphnia. However, this can be attributed more to the
PCNB component (bluegill sunfish: LC50 0.1 mg/L, EPA
designation “highly toxic”) than to etridiazole (LC50
3.27 mg/L, “moderately toxic”). Risk in practice would be mitigated by the use pattern of the product involving
in-furrow soil application.
Waste Disposal
Incineration would be an
effective disposal procedure where permitted. If an efficient
incinerator is not available, the product should be mixed
with large amounts of combustible material and contact
with the smoke should be avoided. In accordance with
40CFR165, follow recommendations for the disposal of
pesticides and pesticide containers
Check Digit Verification of cas no
The CAS Registry Mumber 2593-15-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,9 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2593-15:
(6*2)+(5*5)+(4*9)+(3*3)+(2*1)+(1*5)=89
89 % 10 = 9
So 2593-15-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3
2593-15-9Relevant articles and documents
Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents
-
, (2008/06/13)
Novel optically active Δ1-pyrrolines of the formula (I) in which R1, R2, R1, R4, and m are each as defined in the description, a plurality of the processes for preparing these substances and their use for controlling pests.
Delta 1-pyrrolines used as pesticides
-
, (2008/06/13)
Novel Δ1-pyrrolines of the formula (I) in which R1, R2, R3, m and Q have the meanings given in the description, a plurality of processes for preparing these substances and their use for controlling pests.
Halogen pyrimidinyl aryl (thio)ethers as pesticides
-
, (2008/06/13)
The invention relates to novel halogenopyrimidines, to two processes for their preparation and to their use as pesticides.
