260247-89-0

Basic information

• Product Name: (2-methyl-5,6,7,8-tetrahydroquinolin-3-yl)(phenyl)methanone
• Synonyms: (2-methyl-5,6,7,8-tetrahydroquinolin-3-yl)(phenyl)methanone
• CAS NO: 260247-89-0
• Molecular Weight: 251.328
• Mol File: 260247-89-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-methyl-5,6,7,8-tetrahydroquinolin-3-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methyl-5,6,7,8-tetrahydroquinolin-3-yl)(phenyl)methanone(260247-89-0)
• EPA Substance Registry System: (2-methyl-5,6,7,8-tetrahydroquinolin-3-yl)(phenyl)methanone(260247-89-0)

Safety Data

• Hazardous Substances Data: 260247-89-0(Hazardous Substances Data)

Upstream product

• 93-91-4 1-phenylbutan-1,3-dione 
• 23652-90-6 3-amino-1-phenylbut-2-en-1-one 
• 823-45-0 2-(hydroxymethylene)cyclohexanone 

Relevant articles and documents

Mannich bases as enone precursors for water-mediated efficient synthesis of 2,3,6-trisubstituted pyridines and 5,6,7,8-tetrahydroquinolines

A highly efficient, regioselective, and environmentally friendly method has been developed for water-mediated synthesis of 2,3,6-trisubstituted pyridines and 5,6,7,8-tetrahydroquinolines. The introduced method allows easy preparation of various polysubstituted pyridines and 5,6,7,8-tetrahydroquinolines via domino reaction of an enolizable ketone, ammonia and enones derived from different Mannich bases in mild reaction conditions. Montmorillonite K-10 promoted this one-pot three-component reaction and gave both new and known 2,3,6-trisubstituted pyridines and 5,6,7,8-tetrahydroquinolines in good yields. The reaction protocol provides a wide array of functionality in construction of polysubstituted pyridines and 5,6,7,8-tetrahydroquinolines from commercially available starting materials in easily applicable and environmentally friendly conditions.