261729-68-4

Basic information

• Product Name: 1-(Cbz-alanylglycyl)-3,5-dimethylpyrazole
• CAS NO: 261729-68-4
• Molecular Weight: 358.397
• Mol File: 261729-68-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(Cbz-alanylglycyl)-3,5-dimethylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Cbz-alanylglycyl)-3,5-dimethylpyrazole(261729-68-4)
• EPA Substance Registry System: 1-(Cbz-alanylglycyl)-3,5-dimethylpyrazole(261729-68-4)

Safety Data

• Hazardous Substances Data: 261729-68-4(Hazardous Substances Data)

Upstream product

• 2503-32-4 ethyl N-(benzyloxycarbonyl)-L-alanylglycinate 
• 87023-87-8 1-(Cbz-alanyl)-3,5-dimethylpyrazole 
• 17350-66-2 N-benzyloxycarbonylalaninehydrazid 
• 60625-90-3 Cbz-alanine ethyl ester 
• 28819-05-8 (S)-2-benzyloxycarbonylamino-propionic acid methyl ester 
• 1142-20-7 N-Cbz-Ala 
• 58651-28-8 benzyloxycarbonylalanyl-glycine hydrazide 
• 123-54-6 acetylacetone 

Downstream Products

• 3057-56-5 Cbz-alanylglycylglycyl hydrazide 

Relevant articles and documents

New system for peptide synthesis using N-acylpyrazoles

New system of peptide synthesis was described. The extension of one amino acid unit on the peptide chain was constituted from only 2 reaction steps, the conversion from esters to the corresponding N-acylpyrazoles and the subsequent aminolysis with amino esters. This new system was distinctive from the conventional peptide synthesis, which was consisted of 3 steps of the deprotection, the activation and the condensation. Moreover, the key intermediate N-acylpyrazoles exhibited the excellent properties of high sensitivity and separability for the chiral column on HPLC using the UV detector.