26362-25-4 Usage
Description
(20ξ,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7,24-dien-6-one is a complex steroidal compound that is a derivative of cholesterol. It features a unique pentahydroxy structure with five hydroxyl groups attached to the carbon chain, along with a double bond in its molecular structure. This cholesterol metabolite plays a role in various biological processes and serves as a precursor in the synthesis of essential hormones, including vitamin D.
Uses
Used in Pharmaceutical Industry:
(20ξ,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7,24-dien-6-one is utilized as an intermediate in the synthesis of pharmaceuticals for its unique structural properties and potential therapeutic applications. Its role as a cholesterol metabolite and precursor to hormone synthesis makes it a valuable compound in developing medications targeting various health conditions.
Used in Hormone Research:
In the field of endocrinology and hormone research, (20ξ,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7,24-dien-6-one serves as a key compound for studying the synthesis and regulation of hormones derived from cholesterol. Understanding its role in hormone production can lead to advancements in treatments for hormonal imbalances and related disorders.
Used in Vitamin D Synthesis:
As a precursor to vitamin D, (20ξ,22R)-2β,3β,14,20,22-Pentahydroxy-5β-cholesta-7,24-dien-6-one is crucial in the study and production of vitamin D supplements. Its involvement in the synthesis process makes it an important compound for research into vitamin D deficiency and the development of treatments to address it.
Check Digit Verification of cas no
The CAS Registry Mumber 26362-25-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,3,6 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 26362-25:
(7*2)+(6*6)+(5*3)+(4*6)+(3*2)+(2*2)+(1*5)=104
104 % 10 = 4
So 26362-25-4 is a valid CAS Registry Number.
26362-25-4Relevant articles and documents
Asymmetric dihydroxylation of stachysterone C: Stereoselective synthesis of 24-epi-abuasterone
Yingyongnarongkul, Boon-Ek,Suksamrarn, Apichart
, p. 2795 - 2800 (1998)
Stachysterone C was synthesized from 20-hydroxyecdysone (20-ECD). Sharpless asymmetric dihydroxylation of this rare ecdysteroid using osmium tetroxide and a chiral ligand afforded 24-epi-abutasterone, another rare ecdysteroid, and its C-24 epimer, abutasterone. High diastereomeric excess of the former ecdysteroid was obtained when the chiral ligands dihydroquinidine 1,4-phthalazinediyl diether and dihydroquinidine 2,5-diphenyl-4,6-pyrimidinediyl diether were employed. The two C-24 epimeric ecdysteroids exhibited similar moulting hormone activity in the Musca bioassay. However, they were significantly less active than 20-ECD.
Naturally occurring 20, 26-dihydroxyecdysone exists as two C-25 epimers which exhibit different degrees of moulting hormone activity
Suksamrarn, Apichart,Yingyongnarongkul, Boon-Ek,Promrangsan, Nart
, p. 14565 - 14572 (2007/10/03)
20,26-Dihydroxyecdysone (20,26-ECD) isolated from Vitex canescens, V. glabrata and V. pinnata has been shown to exist as two C-25 epimers. Synthesis and separation of the two epimers were accomplished and they exhibited different degree of moulting hormone activity in the Musca assay.
