26458-04-8Relevant articles and documents
Oxidative trifluoromethylation of arylboronates with shelf-stable potassium (trifluoromethyl)trimethoxyborate
Khan, Bilal A.,Buba, Annette E.,Goossen, Lukas J.
supporting information; experimental part, p. 1577 - 1581 (2012/03/10)
Introducing CF3: Arylboronic acid pinacol esters are converted into the corresponding benzotrifluorides with the easy-to-use one-component trifluoromethylating reagent potassium (trifluoromethyl)trimethoxyborate, mediated by copper acetate under an oxygen atmosphere (see scheme). Copyright
Copper electron-transfer induced trifluoromethylation with methyl fluorosulphonyldifluoroacetate
Chen, Qing-Yun,Yang, Guo-Ying,Wu Sheng-Wen
, p. 291 - 298 (2007/10/02)
Treatment of halogen compounds, RX, with methyl fluorosulfonyldifluoroacetate and copper powder in dimethylformamide for 4 h at 65 - 80 deg C resulted in the corresponding trifluoromethylated products, RCF3, in good yield.In the absence of halogen compounds and at 100 deg C, methyl triflone (CF3SO2CH3) was synthesized readily in the 20 - 30percent yield from the same reaction system.The fact that the reaction was suppressed by oxygen, p-dinitrobenzene or in the darkness suggested that a copper-induced electron-transfer process was involved in this new trifluoromethylating system.
