2657-20-7 Usage
General Description
Phenyl(5,6,7,8-tetrahydronaphthalen-2-yl) ketone, also known as tetralin ketone, is a chemical compound with the molecular formula C16H16O. It is commonly used in the production of various pharmaceuticals, fragrances, and other fine chemicals. Tetralin ketone is a pale yellow liquid with a strong aromatic odor, and is known for its high purity and stability. It is typically synthesized through the Friedel-Crafts acylation of tetralin, a process that involves the reaction of tetralin with acyl chloride in the presence of a Lewis acid catalyst. Tetralin ketone has several important applications in the chemical industry due to its versatile properties and is commonly used as a key intermediate in the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 2657-20-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,5 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2657-20:
(6*2)+(5*6)+(4*5)+(3*7)+(2*2)+(1*0)=87
87 % 10 = 7
So 2657-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H16O/c18-17(14-7-2-1-3-8-14)16-11-10-13-6-4-5-9-15(13)12-16/h1-3,7-8,10-12H,4-6,9H2
2657-20-7Relevant articles and documents
Hydrogen bond donor solvents enabled metal and halogen-free Friedel–Crafts acylations with virtually no waste stream
Liu, Guangchang,Xu, Bo
supporting information, p. 869 - 872 (2018/02/09)
We have developed a metal and halogen-free Friedel–Crafts acylation protocol with virtually no waste stream generation. We propose a hydrogen bonding donor solvent will form a hydrogen bonding network and may provide significant rate enhancement for Friedel–Crafts reactions. Trifluoroacetic acid is one of the strongest H-bond donor solvents, which is also volatile and can be easily recovered by distillation without need for reaction workup. Our protocol is a ‘green’ Friedel–Crafts acylation process: 1) the catalyst can be recovered and reused; 2) using halogen free starting material (carboxylic acids anhydride or carboxylic acids); 3) no need for aqueous reaction work-up; 4) minimum or no waste steam generation.
