26839-77-0 Usage
Description
D-Timolol maleate is a white solid with a variety of medical applications due to its pharmacological properties. It is a beta-adrenergic receptor antagonist, which allows it to be used in the treatment of several conditions related to the cardiovascular and ocular systems.
Uses
Used in Cardiovascular Applications:
D-Timolol maleate is used as an antihypertensive agent for the treatment of high blood pressure. It helps to lower blood pressure by blocking the action of certain stress hormones on the heart and blood vessels, leading to a reduction in heart rate and blood vessel constriction.
D-Timolol maleate is also used as an antiarrhythmic agent (class II) for the management of abnormal heart rhythms. It works by stabilizing the electrical activity of the heart, preventing the occurrence of irregular heartbeats and promoting a more regular rhythm.
Furthermore, D-Timolol maleate is used as an antianginal agent for the relief of chest pain (angina) associated with coronary artery disease. It reduces the workload on the heart by decreasing the heart rate and blood pressure, which in turn reduces the oxygen demand of the heart muscle and alleviates angina symptoms.
Used in Ophthalmic Applications:
In the field of ophthalmology, D-Timolol maleate is used as an antiglaucoma agent for the treatment of elevated intraocular pressure and open-angle glaucoma. It works by reducing the production of aqueous humor, the fluid in the front part of the eye, which helps to lower the pressure inside the eye and prevent damage to the optic nerve.
Check Digit Verification of cas no
The CAS Registry Mumber 26839-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,8,3 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 26839-77:
(7*2)+(6*6)+(5*8)+(4*3)+(3*9)+(2*7)+(1*7)=150
150 % 10 = 0
So 26839-77-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H24N4O3S.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-