2688-48-4 Usage
Description
Homogentisic Acid γ-Lactone, with the CAS number 2688-48-4, is a chemical compound that is characterized by its beige fine crystalline powder appearance. It is primarily known for its utility in organic synthesis, making it a valuable component in the creation of various chemical products.
Uses
Used in Organic Synthesis:
Homogentisic Acid γ-Lactone is used as an intermediate in the synthesis of various organic compounds. Its unique chemical structure allows it to serve as a building block for the development of a wide range of products, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Homogentisic Acid γ-Lactone is used as a key component in the development of drugs targeting specific medical conditions. Its role in organic synthesis enables the creation of novel drug candidates with potential therapeutic benefits.
Used in Agrochemical Industry:
Homogentisic Acid γ-Lactone also finds application in the agrochemical industry, where it is utilized in the synthesis of compounds with pesticidal, herbicidal, or fungicidal properties. This contributes to the development of more effective and environmentally friendly solutions for crop protection and management.
Used in Specialty Chemicals:
The compound is also employed in the production of specialty chemicals, which are tailored to meet the specific requirements of various industries, such as cosmetics, coatings, and plastics. Its versatility in organic synthesis makes it a valuable asset in the development of innovative and high-performance products.
Synthesis Reference(s)
The Journal of Organic Chemistry, 45, p. 363, 1980 DOI: 10.1021/jo01290a038
Check Digit Verification of cas no
The CAS Registry Mumber 2688-48-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,8 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2688-48:
(6*2)+(5*6)+(4*8)+(3*8)+(2*4)+(1*8)=114
114 % 10 = 4
So 2688-48-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H6O3/c9-6-1-2-7-5(3-6)4-8(10)11-7/h1-3,9H,4H2
2688-48-4Relevant articles and documents
An Efficient Synthesis of Homogentisic Acid
Bloomer, James L.,Damodaran, Kalyani M.
, p. 111 (1980)
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Total synthesis of clavatadine A
Conn, Stephanie J.,Vreeland, Shannon M.,Wexler, Alexandra N.,Pouwer, Rebecca N.,Quinn, Ronald J.,Chamberland, Stephen
, p. 120 - 124 (2015)
The first total synthesis of the potent and selective human blood coagulation factor XIa inhibitor clavatadine A (1) is described. Direct, early-stage guanidinylation enabled rapid, convergent access to an immediate clavatadine A precursor. Concomitant lactone hydrolysis and guanidine deprotection with aqueous acid cleanly provided clavatadine A (1) in only four steps (longest linear sequence, 41-43% overall yield).
Lewis acid promoted synthesis of 2(3H)-benzofuranones
Babu, B. Ravindra,Bali, Shilpika,Sakhuja, Rajeev,Jain, Subhash C.
, p. 2546 - 2548 (2007/10/03)
A Lewis acid promoted one-step synthesis of 2(3H)-benzofuranones via an intramolecular rearrangement of the corresponding substituted O-methoxyacetylbenzenes and coumarins is described.
Ketene S,N-Acetals as Synthetic Intermediates for Heterocycles. Reaction of Ketene S,N-Acetals with 1,4-Quinones
Takahata, Hiroki,Anazawa, Akira,Moriyama, Keiko,Yamazaki, Takao
, p. 1501 - 1504 (2007/10/02)
Annelation of ketene S,N-acetals with 1,4-quinones is found to give benzo- and naphthofurans bearing enamine groups.Subsequent enamine reaction allows the formation of 1-benz- and naphthooxepines and benzofuran-2-ones.
