26928-11-0

Basic information

• Product Name: (E)-2-fluoro-3-(4-methoxyphenyl)acrylic acid
• Synonyms: (E)-2-fluoro-3-(4-methoxyphenyl)acrylic acid
• CAS NO: 26928-11-0
• Molecular Weight: 196.178
• Mol File: 26928-11-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-fluoro-3-(4-methoxyphenyl)acrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-fluoro-3-(4-methoxyphenyl)acrylic acid(26928-11-0)
• EPA Substance Registry System: (E)-2-fluoro-3-(4-methoxyphenyl)acrylic acid(26928-11-0)

Safety Data

• Hazardous Substances Data: 26928-11-0(Hazardous Substances Data)

Upstream product

• 26927-87-7 (E)-ethyl 2-fluoro-3-(4-methoxyphenyl)-2-propenoate 

Downstream Products

• 26928-12-1 (Z)-2-fluoro-3-(4-methoxyphenyl)-2-propenoic acid 
• 130490-08-3 (Z)-1-bromo-1-fluoro-3-(4-methoxyphenyl)ethylene 
• 130490-09-4 (E)-1-(2-bromo-2-fluorovinyl)-4-methoxybenzene 
• 130490-04-9 (2R,3R)-2,3-Dibromo-2-fluoro-3-(4-methoxy-phenyl)-propionic acid 
• 130490-04-9 (2R,3S)-2,3-Dibromo-2-fluoro-3-(4-methoxy-phenyl)-propionic acid 

Relevant articles and documents

Pd-and Cu-catalyzed stereo-and regiocontrolled decarboxylative/C-H fluoroalkenylation of heteroarenes

Pd/Cu-catalyzed decarboxylative/direct C-H alkenylations of heteroarenes with α-fluoroacrylic acid is reported. This method offers step-economical and stereocontrolled access to valuable heteroarylated monofluoroalkenes as both Z and E isomers, which are known to be useful in the synthesis of fluorinated biomolecules.