2718-25-4 Usage
Description
Rhoeadine is an isoquinoline alkaloid derived from Papaver rhoeas Linn (red poppy) and was initially thought to be present in opium. It is characterized by its weak basic properties, sparing solubility in water, alkaline solutions, and most organic solvents. Rhoeadine exhibits unique optical activity and contains two methylenedioxy groups, one methoxy group, and an N-methyl group. The alkaloid is known for its intensely red solution when dissolved in mineral acids, with a significant portion being converted into a colorless, crystalline substance called Rhoeagenine, which is a stronger base and more stable to acids.
Uses
Used in Pharmaceutical Applications:
Rhoeadine is used as a therapeutic agent for the prevention and treatment of pathologies involving central and/or peripheral disorders. Its isoquinoline alkaloid structure contributes to its potential applications in the medical field.
Used in Research and Development:
The unique properties of Rhoeadine, such as its optical activity and the formation of Rhoeagenine, make it an interesting compound for research and development in the fields of chemistry and pharmacology. Further studies on its structure, properties, and potential applications can lead to the discovery of new therapeutic agents and drug delivery systems.
References
Hesse., Annalen, Suppl., 4, 50 (1S65)
Hesse., ibid, 140, 145 (1S66)
Spath., Monatsh., 68,33 (1936)
Awe., Arch. Pharm., 279,116 (1941)
Santavy etat., Collect. Czech. Chem. Commun., 30,335,3479 (1965)
Mass spectrum:
Dolejs, Hanus., Tetrahedron, 23, 2997 (1967)
Stereochemistry:
Shamma et at., Chem. Commun., 212 (1968)
Check Digit Verification of cas no
The CAS Registry Mumber 2718-25-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,1 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2718-25:
(6*2)+(5*7)+(4*1)+(3*8)+(2*2)+(1*5)=84
84 % 10 = 4
So 2718-25-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H21NO6/c1-22-6-5-11-7-15-16(26-9-25-15)8-13(11)19-18(22)12-3-4-14-20(27-10-24-14)17(12)21(23-2)28-19/h3-4,7-8,18-19,21H,5-6,9-10H2,1-2H3/t18-,19-,21+/m1/s1
2718-25-4Relevant articles and documents
6-(3,4-Methylenedioxy-6-benzylalkylaminoethylphenylacetyl)benzoic acid alkyl ester derivatives
-
, (2008/06/13)
The present invention relates to the preparation of novel rheadan-type alkaloids and to novel intermediates useful in the preparation thereof. The process utilizes as starting materials a known class of alkaloids of the narcotine or of the hydrastine type. Certain of the said novel intermediates are also pharmaceutically useful in and of themselves. Additionally, certain of the novel intermediates can be converted into other type alkaloids which are also pharmaceutically useful.
