2719-13-3

Basic information

• Product Name: 4-Nitrophenylacethydrazide
• Synonyms: 4-Nitrophenylacethydrazide;N'-(4-Nitrophenyl)acetohydrazide;N'-(p-Nitrophenyl)acetohydrazide
• CAS NO: 2719-13-3
• Molecular Formula: C₈H₉N₃O₃
• Molecular Weight: 195.17536
• Mol File: 2719-13-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 331.83°C (rough estimate)
• Flash Point: 139.9°C
• Appearance: /
• Density: 1.3620 (rough estimate)
• Refractive Index: 1.7400 (estimate)
• CAS DataBase Reference: 4-Nitrophenylacethydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Nitrophenylacethydrazide(2719-13-3)
• EPA Substance Registry System: 4-Nitrophenylacethydrazide(2719-13-3)

Safety Data

• Hazardous Substances Data: 2719-13-3(Hazardous Substances Data)

Usage

Safety Profile

Poison by ingestion. When heatedto decomposition it emits toxic vapors of NOx.

Upstream product

• 507-09-5 thioacetic acid 
• 108-94-1 cyclohexanone 
• 64-19-7 acetic acid 
• 100-16-3 4-nitrophenylhydrazone 
• 861801-83-4 4,4-bis-[N'-(4-nitro-phenyl)-hydrazino]-pentan-2-one 
• 625-77-4 N-acetylacetamide 
• 463-51-4 Ketene 
• 113407-66-2 2-(4-nitrophenylhydrazino)tetrahydrofuran 
• 70638-46-9 2,5-dimethyl-2-(4-nitro-phenylazo)-furan-3-one 
• 27182-39-4 5-methyl-3-(4-nitro-phenyl)-3H-[1,3,4]oxadiazol-2-one 
• 23460-22-2 triacetyl-(4-nitro-phenyl)-hydrazine 
• 113407-52-6 4-Chloro-butyric acid N'-(4-nitro-phenyl)-hydrazide 
• 100-05-0 4-nitrobenzenediazonium chloride 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 

Downstream Products

• 857796-35-1 N'-acetyl-N-chloroacetyl-N-(4-nitro-phenyl)-hydrazine 
• 27182-39-4 5-methyl-3-(4-nitro-phenyl)-3H-[1,3,4]oxadiazol-2-one 
• 13122-36-6 nitrobenzene-4-d 
• 1694-20-8 trans-4-nitrostilbene 
• 787-64-4 2-(4-nitrophenyl)-1-benzofurane 

Relevant articles and documents

Palladium/copper-catalyzed arylation of alkenes with N′-acyl arylhydrazines

A novel ligand-free palladium/copper-catalyzed Heck-type coupling reaction of alkenes and N′-acyl arylhydrazines has been developed by using air as the terminal oxidant. This protocol features wide functional group tolerance and produces highly chemoselective and regioselective products with good to excellent yields.

PREPARATION OF N-ARYLAMINO-2-PYRROLIDONES FROM ARYLHYDRAZIDES OF γ-CHLOROBUTYRIC ACID

Intramolecular alkylation of the arylhydrazides of γ-chlorobutyric acid in the presence of sodium ethoxide leads to the formation of N-arylamino-2-pyrrolidones.The direction of the reaction is not altered by the absence of a substituent on the aniline nitrogen atom.In the case of a p-nitrophenyl-hydrazide, O-alkylation is observed.

REACTION OF 2-ARYLAZO-2,5-DIMETHYL-3(2H)-FURANONES WITH AMMONIA. PREPARATION OF β-ACETYL-β-(3-AMINO-2-BUTENOYL)ARYLHYDRAZINES.

Ring opening of 2-arylazo-2,5-dimethyl-3(2H)-furanones (1a-d) with ammonia leads to previously unknown β-acetyl-β-(3-amino-2-butenoyl)arylhydrazines (3a-d).The reaction mechanism is discussed.