274-78-2 Usage
General Description
Imidazo[1,2-c]pyrimidine is a heterocyclic compound with a fused imidazole-pyrimidine ring structure. It is commonly used as a core scaffold in the design and synthesis of various pharmaceuticals and agrochemicals due to its potential biological activities. Imidazo[1,2-c]pyrimidine derivatives have been reported to exhibit a wide range of pharmacological activities, including antiviral, anticancer, antifungal, antihypertensive, and anti-inflammatory properties. These compounds have also been investigated for their potential use in treating neurological disorders and as inhibitors of protein kinases. Due to their diverse biological activities, Imidazo[1,2-c]pyrimidine derivatives hold promise as lead compounds for the development of new therapeutic agents in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 274-78-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,7 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 274-78:
(5*2)+(4*7)+(3*4)+(2*7)+(1*8)=72
72 % 10 = 2
So 274-78-2 is a valid CAS Registry Number.
274-78-2Relevant articles and documents
Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases
Linz, Sabine,Mueller, Joerg,Huebner, Harald,Gmeiner, Peter,Troschuetz, Reinhard
scheme or table, p. 4448 - 4458 (2009/12/04)
A series of phenylpiperazine-methyl-substituted 1H-pyrrolo[2,3-c]pyridine, imidazo[1,2-c]-, pyrrolo[2,3-d]- and pyrrolo[3,2-d]pyrimidines were prepared as selective dopamine D4-ligands. The pyrrolo[2,3-d]pyrimidine derivatives 12d (Ki = 1,9 nM)