28049-59-4

Basic information

• Product Name: 1-(2-Chlorophenyl)cyclobutanecarbonitrile
• Synonyms: 1-(2-Chlorophenyl)cyclobutanecarbonitrile;CYCLOBUTANECARBONITRILE, 1-(2-CHLOROPHENYL)-
• CAS NO: 28049-59-4
• Molecular Formula: C₁₁H₁₀ClN
• Molecular Weight: 191.6568
• Mol File: 28049-59-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(2-Chlorophenyl)cyclobutanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Chlorophenyl)cyclobutanecarbonitrile(28049-59-4)
• EPA Substance Registry System: 1-(2-Chlorophenyl)cyclobutanecarbonitrile(28049-59-4)

Safety Data

• Hazardous Substances Data: 28049-59-4(Hazardous Substances Data)

Usage

General Description

1-(2-Chlorophenyl)cyclobutanecarbonitrile is a chemical compound with the molecular formula C11H8ClN. It belongs to the class of cyclobutane-containing compounds and has a chlorophenyl group attached to the cyclobutane ring. 1-(2-Chlorophenyl)cyclobutanecarbonitrile is a carbonitrile, meaning it contains a nitrile functional group (–C≡N). It is used in organic synthesis and can be utilized in the preparation of various pharmaceuticals and agrochemicals. Additionally, it has been studied for its potential biological activities, including its role as an enzyme inhibitor. Overall, 1-(2-Chlorophenyl)cyclobutanecarbonitrile is a versatile compound with important applications in different fields of chemistry and biology.

Upstream product

• 2856-63-5 2-Chlorophenylacetonitrile 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 151157-45-8 C₁₁H₁₁ClO₂ 
• 29786-24-1 (<1-(o-Chlorophenyl)cyclobutyl>carbonyl)carbamsaeureethylester 
• 29770-98-7 (<1-(o-Chlorophenyl)cyclobutyl>carbonyl)carbamsaeuremethylester 
• 29770-30-7 (<1-(o-Chlorophenyl)-cyclobutyl>-carbonyl)-harnstoff 
• 29771-01-5 <1-(o-Chlorophenyl)cyclobutyl>carbonylisocyanat 
• 29771-00-4 1-(2-chlorophenyl)cyclobutane-1-carboxamide 

Relevant articles and documents

Synthesis method of arylcyclobutane compound

The present invention discloses a method for synthesizing an arylcyclobutane compound to 1eq phenylacetonitrile and 1.1eq 1-bromo-3-chloropropane as raw material, N,N- dimethylacetamide as a solvent, plus 2.5eq sodium hydride, under the protection of iner

Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO)

N-(5-Chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutanecarboxamide (N-CDPCB, 1a) is found to be an inhibitor of the fat mass and obesity associated protein (FTO). The crystal structure of human FTO with 1a reveals a novel binding site for the FTO inhibitor and defines the molecular basis for recognition by FTO of the inhibitor. The identification of the new binding site offers new opportunities for further development of selective and potent inhibitors of FTO, which is expected to provide information concerning novel therapeutic targets for treatment of obesity or obesity-associated diseases.