28220-12-4

Basic information

• Product Name: 5'-Adenylic acid, 2'-(4-methylbenzenesulfonate)
• CAS NO: 28220-12-4
• Molecular Formula: C17H20N5O9PS
• Molecular Weight: 501.414
• Mol File: 28220-12-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5'-Adenylic acid, 2'-(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-Adenylic acid, 2'-(4-methylbenzenesulfonate)(28220-12-4)
• EPA Substance Registry System: 5'-Adenylic acid, 2'-(4-methylbenzenesulfonate)(28220-12-4)

Safety Data

• Hazardous Substances Data: 28220-12-4(Hazardous Substances Data)

Upstream product

• 61-19-8 5'-adenosine monophosphate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 29984-33-6 vidarabine monophosphate 

Relevant articles and documents

Synthesis method and application of vidarabine monophosphate

The invention belongs to the field of medicine synthesis, and discloses a synthesis method and application of vidarabine monophosphate. According to the synthesis method, 5-iodo-2-((phosphonooxy) methyl)-4-(tosyloxy)tetrahydrofuran-3-yl acetate and tert-butyl (8-hydroxy-9H-purin-6-yl)carbamate are subjected to condensation, epoxidation, ring opening and desulfurization reaction, and the vidarabine monophosphate is synthesized. According to the synthesis method of vidarabine monophosphate, provided by the invention, the industrial production steps are further simplified, the total reaction yield is improved, and the industrial production cost is reduced. The method is suitable for synthesizing vidarabine monophosphate, and the synthesized vidarabine monophosphate is used for preparing vidarabine monophosphate for injection.