28396-55-6

Basic information

• Product Name: Naphthalene, 2-(4-fluorophenyl)-
• CAS NO: 28396-55-6
• Molecular Formula: C16H11F
• Molecular Weight: 222.262
• Mol File: 28396-55-6.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: Naphthalene, 2-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 2-(4-fluorophenyl)-(28396-55-6)
• EPA Substance Registry System: Naphthalene, 2-(4-fluorophenyl)-(28396-55-6)

Safety Data

• Hazardous Substances Data: 28396-55-6(Hazardous Substances Data)

Upstream product

• 732306-64-8 bis(4-fluorophenyl)iodonium triflate 
• 91-20-3 naphthalene 
• 17666-88-5 1-(naphthalen-2-yl)butan-1-one 
• 352-13-6 4-flourophenylmagnesium bromide 
• 1173294-78-4 2-(4-fluorophenoxy)pyridine 
• 21473-01-8 2-naphthalenylmagnesium bromide 
• 371-41-5 4-Fluorophenol 
• 580-13-2 2-bromonaphthalene 
• 1765-93-1 4-fluoroboronic acid 
• 91-58-7 2-chloronaphthalene 
• 133472-27-2 4-fluorophenylzinc chloride 
• 13198-35-1 trimethyl-[2]naphthyl-ammonium; iodide 
• 1493-23-8 (4-fluorophenyl)lithium 
• 2436-85-3 2-N,N-Dimethylaminonaphthalene 

Relevant articles and documents

Arylketones as Aryl Donors in Palladium-Catalyzed Suzuki-Miyaura Couplings

Herein, we report the arylation, alkylation, and alkenylation of aryl ketones via a palladium-catalyzed Suzuki-Miyaura cross-coupling reaction. The use of the pyridine-oxazoline ligand is the key to the cleavage of the unstrained C-C bond. The late-stage arylation of aryl ketones derived from drugs and natural products demonstrated the synthetic utility of this protocol.

Desulfurization of Diaryl(heteroaryl) Sulfoxides with Benzyne

Two benzyne-enabled desulfurization reactions have been demonstrated which convert diaryl sulfoxides and heteroaryl sulfoxides to biaryls and desulfurized heteroarenes, respectively. The reaction accessing biaryls tolerates a variety of functional groups, such as halides, pseudohalides, and carbonyls. Mechanistic studies reveal that both reactions proceed via a common assembly process but divergent disassemblies of the generated tetraaryl(heteroaryl) sulfuranes.

Room-Temperature Aqueous Suzuki-Miyaura Cross-Coupling Reactions Catalyzed via a Recyclable Palladium@Halloysite Nanocomposite

A reliable method for encapsulation of palladium nanoparticles (6-8 nm particles) in halloysite (Pd@Hal) has been developed. The Pd@Hal was found to be a highly efficient room-temperature catalyst for Suzuki-Miyaura cross-coupling reactions that gave high yields of a diverse array of coupling products in 5:2 n-PrOH/H2O within 1 h. The catalytic system was remarkably effective with a broad substrate scope. In addition, the catalyst was easily recovered and recycled without a significant loss of catalytic activity.