28509-46-8

Basic information

• Product Name: 2-Butanone, 4-bromo-
• Synonyms: 4-bromo-butan-2-one;Methyl-(2-brom-aethyl)-keton;2-bromoethyl(methyl)ketone;2-Butanone,4-bromo;4-bromo-2-butanone;1-ACETYL-2-BROMOETHANE;2-acetoyl ethyl bromide;bromomethyl acetone;4-Brom-butan-2-on
• CAS NO: 28509-46-8
• Molecular Formula: C4H7BrO
• Molecular Weight: 151.003
• Mol File: 28509-46-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 59 °C(Press: 12 Torr)
• Density: 1.439±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Butanone, 4-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-bromo-(28509-46-8)
• EPA Substance Registry System: 2-Butanone, 4-bromo-(28509-46-8)

Safety Data

• Hazardous Substances Data: 28509-46-8(Hazardous Substances Data)

Upstream product

• 5162-44-7 1-bromo-4-butene 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 107-21-1 ethylene glycol 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 34047-39-7 4-methylsulfanyl-2-butanone 
• 61224-82-6 4-ethylthio-butan-2-one 
• 137296-27-6 7-(4-Methoxy-benzyl)-1-(3-oxo-butyl)-3-propyl-3,7-dihydro-purine-2,6-dione 
• 37865-96-6 2-(2-bromoethyl)-2-methyl-1,3-dioxolane 
• 927-56-0 levulinonitrile 
• 264599-22-6 benzyl 2-benzyloxicarbonyl-5-oxohexanoate 

Relevant articles and documents

Palladium-Catalyzed Aerobic Anti-Markovnikov Oxidation of Aliphatic Alkenes to Terminal Acetals

Terminal acetals were selectively synthesized from various unbiased aliphatic terminal alkenes and 1,2-, 1,3-, or 1,4-diols using a PdCl2(MeCN)2/CuCl catalyst system in the presence of p-toluquinone under 1 atm of O2 and mild reaction conditions. The slow addition of terminal alkenes suppressed the isomerization to internal alkenes successfully. Electron-deficient cyclic alkenes, such as p-toluquinone, were key additives to enhance the catalytic activity and the anti-Markovnikov selectivity. The halogen groups in the alkenes were found to operate as directing groups, suppressing isomerization and increasing the selectivity efficiently.