286-22-6

Basic information

• Product Name: 3,7-DIOXABICYCLO[4.1.0]HEPTANE
• Synonyms: 3,7-DIOXABICYCLO[4.1.0]HEPTANE;3,4-Epoxytetrahydropyran
• CAS NO: 286-22-6
• Molecular Formula: C₅H₈O₂
• Molecular Weight: 100.12
• Mol File: 286-22-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 167.7±8.0 °C(Predicted)
• Appearance: /
• Density: 1.146±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 3,7-DIOXABICYCLO[4.1.0]HEPTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,7-DIOXABICYCLO[4.1.0]HEPTANE(286-22-6)
• EPA Substance Registry System: 3,7-DIOXABICYCLO[4.1.0]HEPTANE(286-22-6)

Safety Data

• Hazardous Substances Data: 286-22-6(Hazardous Substances Data)

Usage

General Description

3,7-Dioxabicyclo[4.1.0]heptane is a chemical compound that is classified under a class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups. However, specific information about its uses, properties, and toxicology is currently limited or non-existent in common chemical information databases. Therefore, caution should be exercised when handling or using this chemical until more comprehensive data is available.

Upstream product

• 134419-59-3 4-oxanyl methanesulfonate 
• 2081-44-9 Tetrahydro-pyran-4-ol 
• 25637-16-5 4-bromotetrahydro-2H-pyran 
• 3174-74-1 dihydropyran 

Downstream Products

• 1096594-11-4 3-amino-1,5-anhydro-2,3-dideoxy-L-threo-pentitol hydrochloride 
• 1363380-59-9 trans-4-aminotetrahydro-2H-pyran-3-ol 
• 1309081-45-5 rac-(3R,4S)-3-aminotetrahydro-2H-pyran-4-ol 
• 1309081-45-5 (3,4-cis)-3-amino-tetrahydro-pyran-4-ol 
• 1309081-45-5 (3,4-cis)-3-amino-tetrahydro-pyran-4-ol 
• 1309081-45-5 (3S,4S)-3-aminotetrahydro-2H-pyran-4-ol 
• 1363380-59-9 (3R,S),(4R,S)-4-aminotetrahydropyran-3-ol 
• 1309081-45-5 (3,4-cis)-3-aminotetrahydropyran-4-ol 

Relevant articles and documents

Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols

Traditional approaches to stereoselective synthesis require high levels of enantio- and diastereocontrol in every step that forms a new stereocenter. Here, we report an alternative approach, in which the stereochemistry of organic substrates is selectivel

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

6-[5-AMINO-6-(2-ETHOXYETHOXY)-IMIDAZO[4,5-B]PYRIDIN-3-YL]-NICOTINONITRILE DERIVATIVES AND THEIR USE AS IRAK INHIBITORS

The present invention discloses compounds according to Formula (I): wherein R1, R2, and Cy are as defined herein. The present invention relates to compounds inhibiting IRAK family kinases, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases and/or proliferative diseases by administering the compound of the invention.