288621-65-8

Basic information

• Product Name: N-[2-[(4bS,8R,8aS,14bR)-7-(Cyclopropylmethyl)-1,8a-dihydroxy-5,6,7,8,8a,9,14,14b-octahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazol-11-yl]ethyl]acetamidine
• Synonyms: ANTI; N-[2-[17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-6,7-didehydroindolo[ 2',3':6,7]morphinan-5'-yl]ethyl]acetamidine
• CAS NO: 288621-65-8
• Molecular Formula: C₃₀H₃₄N₄O₃
• Molecular Weight: 498.63048
• Mol File: 288621-65-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[2-[(4bS,8R,8aS,14bR)-7-(Cyclopropylmethyl)-1,8a-dihydroxy-5,6,7,8,8a,9,14,14b-octahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazol-11-yl]ethyl]acetamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-[(4bS,8R,8aS,14bR)-7-(Cyclopropylmethyl)-1,8a-dihydroxy-5,6,7,8,8a,9,14,14b-octahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazol-11-yl]ethyl]acetamidine(288621-65-8)
• EPA Substance Registry System: N-[2-[(4bS,8R,8aS,14bR)-7-(Cyclopropylmethyl)-1,8a-dihydroxy-5,6,7,8,8a,9,14,14b-octahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazol-11-yl]ethyl]acetamidine(288621-65-8)

Safety Data

• Hazardous Substances Data: 288621-65-8(Hazardous Substances Data)

Upstream product

• 288621-84-1 5'-cyanomethyl-17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-3,14-dihydroxy-indolo[2',3':6,7]morphinan 
• 16676-29-2 naltrexone Hydrochloride 
• 57411-91-3 4-(cyanomethyl)phenylhydrazine 
• 14777-27-6 methyl acetimidate hydrochloride 
• 288621-59-0 5'-(2-aminoethyl)-17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan 
• 2208-07-3 ethyl acetimidate hydrochloride 

Relevant articles and documents

The role of the side chain in determining relative δ- and κ-affinity in C5′-substituted analogues of naltrindole

The role of the side chain in 5′-substituted analogues of naltrindole has been further explored with the synthesis of series of amides, amidines, and ureas. Amidines (8, 13) had greatest selectivity for the K receptor, as predicted from consideration of the message-address concept. It was also found that an appropriately located carbonyl group, in ureas (10) and amides (7), led to retention of affinity and antagonist potency at the δ receptor.