28876-38-2

Basic information

• Product Name: 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE
• Synonyms: 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE;2-(Acetylamino)-2-deoxy-D-galactonic Acid -Lactone
• CAS NO: 28876-38-2
• Molecular Formula: C8H13NO6
• Molecular Weight: 219.19192
• Product Categories: 13C & 2H Sugars;Amines;Carbohydrates & Derivatives;Amines, Carbohydrates & Derivatives
• Mol File: 28876-38-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 162-166°C
• Appearance: /
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• CAS DataBase Reference: 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE(28876-38-2)
• EPA Substance Registry System: 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE(28876-38-2)

Safety Data

• Hazardous Substances Data: 28876-38-2(Hazardous Substances Data)

Usage

Description

2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE, also known as Galactonic acid derivative, is a crystalline solid with unique chemical properties. It is a derivative of galactonic acid and is characterized by the presence of an acetamido group and a deoxy function in its molecular structure. 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE has potential applications in various industries due to its distinctive chemical and biological properties.

Uses

Used in Pharmaceutical Industry:
2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE is used as an N-acetylglucosaminidase inhibitor for the treatment of various diseases. As an inhibitor, it helps regulate the activity of the enzyme N-acetylglucosaminidase, which is involved in the metabolism of glycoproteins and glycolipids. Modulating the activity of this enzyme can have therapeutic benefits in conditions where the enzyme's activity is dysregulated.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE can be used as a building block or intermediate for the synthesis of more complex molecules. Its unique structure and functional groups make it a valuable component in the development of novel compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
2-ACETAMIDO-2-DEOXY-D-GALACTONIC ACID1,4 -LACTONE is also utilized in research and development for studying the structure, properties, and potential applications of galactonic acid derivatives. Its crystalline solid form allows for easy handling and manipulation in laboratory settings, making it a useful compound for exploring new chemical reactions and understanding the underlying mechanisms of various biological processes.

Upstream product

• 72-87-7 N-acetyl-D-galactosamine 
• 87924-40-1 2-acetamido-2-deoxy-D-galactose N,N'-diphenylformazan 
• 1948-54-5 D-galactosamine 
• 81176-80-9 D-galactosaminic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 34044-52-5 2-acetylamino-O⁵,O⁶-isopropylidene-2-deoxy-D-galactonic acid-4-lactone 
• 10486-91-6 2-acetamido-2-deoxy-D-galacticol 

Relevant articles and documents

2-Acetamido-2-deoxyaldonolactones from sugar formazans

A new approach towards simple aldonic acid derivatives starting from the corresponding aldoses via the 2-acetamido-2-deoxy formazans resulted in the synthesis of 2-acetamido-2-deoxy-D-galactono-1,4-lactone (8), and its 6-deoxy (11) and 6-azido-6-deoxy (14) analogues on treatment with trifluoroacetic acid.The five-membered ring structure of the lactones and that of the intermediate lactone phenylhydrazone (7) was proved by 1H and 13C NMR studies, including deuterium-induced differential isotope shift (DIS) measurements.With sodium borohydride, lactones 8 and 11 were converted into 2-acetamido-2-deoxy-D-galactitol (15) and its 6-deoxy analogue (17), respectively.