29117-54-2

Basic information

• Product Name: (S)-1,2-PENTANEDIOL
• Synonyms: (S)-1,2-PENTANEDIOL;(2S)-1,2-Pentanediol;(2S)-Pentane-1,2-diol;(S)-Pentane-1,2-diol
• CAS NO: 29117-54-2
• Molecular Formula: C₅H₁₂O₂
• Molecular Weight: 104.15
• Mol File: 29117-54-2.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 83.0-84.5℃ (7 Torr)
• Flash Point: 101.7 °C
• Appearance: /
• Density: 0.974 g/cm³
• Refractive Index: 1.4356 (18℃)
• CAS DataBase Reference: (S)-1,2-PENTANEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1,2-PENTANEDIOL(29117-54-2)
• EPA Substance Registry System: (S)-1,2-PENTANEDIOL(29117-54-2)

Safety Data

• Hazardous Substances Data: 29117-54-2(Hazardous Substances Data)

Usage

Description

(S)-1,2-Pentanediol is a colorless, odorless, and viscous liquid chemical compound with the chemical formula C5H12O2. It is classified as a diol, meaning it contains two hydroxyl functional groups. This versatile and multifunctional chemical is widely used across various industries.

Uses

Used in Polymer and Resin Production:
(S)-1,2-Pentanediol is used as a monomer and building block for the production of polymers and resins. Its diol functionality allows it to react with other monomers and form polymer chains, contributing to the properties of the final product.
Used in Adhesive Formulation:
(S)-1,2-Pentanediol is used as a solvent and coupling agent in the formulation of adhesives. Its ability to dissolve and interact with various components helps improve the adhesive's performance and bonding capabilities.
Used in Personal Care Products:
(S)-1,2-Pentanediol is used as a humectant in personal care products, such as skin creams and lotions. Its hygroscopic nature helps retain moisture, providing hydration and improving the skin's appearance.
Used in Pharmaceutical Synthesis:
(S)-1,2-Pentanediol is used as an intermediate in the synthesis of various pharmaceuticals. Its diol functionality allows it to be incorporated into drug molecules, potentially enhancing their therapeutic properties.
Used as a Preservative in Food and Beverage Products:
(S)-1,2-Pentanediol is used as a preservative in food and beverage products due to its antimicrobial properties. It helps prevent spoilage and extends the shelf life of these products.
Used in Application Industry:
(S)-1,2-Pentanediol is used as [application type] for [application reason].

Upstream product

• 41014-93-1 2-(S)-hydroxyvaleric acid 
• 5343-92-0 1,2-pentanediol 
• 81947-72-0 1,2-diacetoxypentane 
• 110352-58-4 (S)-2-Benzyloxy-pentanoic acid methyl ester 
• 167777-55-1 (S)-2-Benzyloxy-pentan-1-ol 
• 88945-70-4 ethyl 2-hydroxy-n-valerate 
• 64-19-7 acetic acid 
• 79364-35-5 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol 
• 584-93-0 2-Bromovaleric acid 
• 110320-67-7 2-Benzyloxy-pentanoic acid methyl ester 
• 100-52-7 benzaldehyde 
• 87604-53-3 (R)-4-((S)-1-(benzyloxy)but-3-ene-1-yl)-2,2-dimethyl-1,3-dioxypentane 
• 99838-68-3 (2R,3S)-3-(benzyloxy)hex-5-ene-1,2-diol 
• 87604-58-8 (S)-(-)-2-Benzyloxypent-4-enal 

Downstream Products

• 104128-62-3 (+)-(2S)-1-O-trityl-1,2-pentanediol 
• 878632-87-2 (S)-2-Phenyl-4-propyl-[1,3]dioxolane 
• 2305-25-1 ethyl (R)-3-hydroxyhexanoate 
• 123731-69-1 Dibenzyl-amine; compound with (S)-3-hydroxy-hexanoic acid 
• 123808-05-9 (1E,4S)-1-(2-bromo-3,4,5-trimethoxyphenyl)-1-hepten-4-ol 
• 30263-96-8 (2S,3R,5S)-5-Propyl-2-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-3-ol 
• 123731-55-5 Toluene-4-sulfonic acid (S)-3-(tert-butyl-dimethyl-silanyloxy)-hexyl ester 
• 28890-33-7 (2S,3aS,9bS)-6-Hydroxy-7,8-dimethoxy-2-propyl-2,3,3a,9b-tetrahydro-furo[3,2-c]isochromen-5-one 
• 28890-33-7 monocerin 
• 123808-07-1 (2S,3R,5S)-2-(2-bromo-3,4,5-trimethoxyphenyl)-5-propyltetrahydrofuran-3-ol 
• 123731-65-7 6-((2S,3R,5S)-3-Hydroxy-5-propyl-tetrahydro-furan-2-yl)-2,3,4-trimethoxy-benzoic acid 
• 123808-04-8 2-bromo-1-<(1E,4S)-4-t-butyldimethylsilyloxy-1-heptenyl>-3,4,5-trimethoxybenzene 
• 123731-59-9 (4S)-1-(2-bromo-3,4,5-trimethoxyphenyl)-4-t-butyldimethylsilyloxy-1-heptanol 
• 123731-58-8 Acetic acid (S)-1-(2-bromo-3,4,5-trimethoxy-phenyl)-4-(tert-butyl-dimethyl-silanyloxy)-heptyl ester 

Relevant articles and documents

Diastereoselective addition of allyltrimethylsilane to N-glyoxyloyl(2R)- bornane-10,2-sultam. A new synthesis of (S)-1,2-pentanediol

Addition of allyltrimethylsilane (3) to N-glyoxyloyl-(2R)-bornane-10,2- sultam (4) in the presence of Lewis acid afforded, in high diastereoselectivity, adduct (2'S')-6 which, after recrystallization, was hydrogenated to give optically pure (S)-1,2-pentanediol (1).

Kinetic Resolution of 1,2-Diols via NHC-Catalyzed Site-Selective Esterification

A kinetic resolution of 1,2-diols bearing both a secondary and a primary alcohol motif through an N-heterocyclic carbene-catalyzed oxidative acylation reaction has been developed. A site- and enantioselective esterification reaction is involved for this process. Both the monoacylated diols obtained and the remaining enantioenriched 1,2-diols are versatile building blocks for the preparation of functional molecules with proven biological activities.

A critical outlook and comparison of enantioselective oxidation methodologies of olefins

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