29778-21-0

Basic information

• Product Name: 1-isopropyl-2-(2-phenylethynyl)benzene
• Synonyms: 1-isopropyl-2-(2-phenylethynyl)benzene
• CAS NO: 29778-21-0
• Molecular Weight: 220.314
• Mol File: 29778-21-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-isopropyl-2-(2-phenylethynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-isopropyl-2-(2-phenylethynyl)benzene(29778-21-0)
• EPA Substance Registry System: 1-isopropyl-2-(2-phenylethynyl)benzene(29778-21-0)

Safety Data

• Hazardous Substances Data: 29778-21-0(Hazardous Substances Data)

Upstream product

• 19099-54-8 2-isopropyliodobenzene 
• 536-74-3 phenylacetylene 
• 591-50-4 iodobenzene 
• 1147014-57-0 [(2-isopropylphenyl)ethynyl]trimethylsilane 
• 7073-94-1 1-bromo-2-isopropylbenzene 
• 98-82-8 Isopropylbenzene 
• 932-88-7 1-iodo-2-phenylethyne 

Downstream Products

• 452094-53-0 C₅H₄NCHCSn(C₄H₉)3C₆H₄(o-CH(CH₃)2) 
• 21866-30-8 1,1-dimethyl-2-phenyl-1H-indene 
• 26465-83-8 1,1-dimethyl-3-phenyl-1H-indene 
• 1418135-72-4 1,1-dimethyl-2-phenyl-3-p-tolyl-1H-indene 
• 1418135-74-6 2-(1,1-dimethyl-2-phenyl-1H-inden-3-yl)thiophene 
• 1418135-73-5 3-(4-methoxyphenyl)-1,1-dimethyl-2-phenyl-1H-indene 
• 18949-22-9 1,1-dimethyl-2,3-diphenyl-1H-indene 
• 1418135-71-3 3-(2-bromophenyl)-1,1-dimethyl-2-phenyl-1H-indene 
• 1418135-70-2 3-(4-iodophenyl)-1,1-dimethyl-2-phenyl-1H-indene 
• 1418135-69-9 3-(4-fluorophenyl)-1,1-dimethyl-2-phenyl-1H-indene 
• 1418135-68-8 3-(4-chlorophenyl)-1,1-dimethyl-2-phenyl-1H-indene 
• 1418135-67-7 1-(4-(1,1-dimethyl-2-phenyl-1H-inden-3-yl)phenyl)ethanone 
• 1418135-66-6 4-(1,1-dimethyl-2-phenyl-1H-inden-3-yl)benzonitrile 
• 1418135-65-5 1,1-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2-phenyl-1H-indene 

Relevant articles and documents

Novel oxime-palladacycle supported on clay composite as an efficient heterogeneous catalyst for Sonogashira reaction

A novel supported catalyst formed by an oxime-derived palladacycle supported on clay OxPdCy@clay is synthesized and characterized. This palladium composite promotes the Sonogashira reaction of aryl iodides, bromides and chlorides with terminal alkynes in polyethylene glycol200 at 85 or 130 °C using 0.05–0.1 mol% of palladium loading under copper and phosphine free conditions. This supported palladacycle, OxPdCy@clay, showed a superior catalytic activity than dimeric oxime-palladacycles. Mechanistic studies about the heterogeneous or homogeneous nature of the catalyst show that catalyst is working mainly under heterogeneous conditions. This supported palladacycle OxPdCy@clay can be recycled by simple centrifugation and reused for at least nine consecutive runs with small decrease in activity.

Intramolecular addition of triarylmethanes to alkynes promoted by KOtBu/DMF: A synthetic approach to indene derivatives

A method for the intramolecular addition of triarylmethanes to alkynes has been developed. The reaction was efficiently promoted by KOtBu/DMF without any transition-metal catalyst. A variety of indene derivatives were prepared in moderate to good yields. A cascade cyclization of 2-alkyl-substituted substrates at elevated reaction temperature gave bicyclic indene derivatives. The reaction is proposed to proceed through the generation of a triphenylmethyl radical. Indene derivatives were prepared by the intramolecular addition of triarylmethanes to alkynes promoted by KOtBu/DMF. A cascade cyclization of 2-alkyl-substituted substrates at elevated reaction temperature gave bicyclic indene derivatives. A free-radical reaction mechanism is proposed.

A guide to sonogashira cross-coupling reactions: The influence of substituents in aryl bromides, acetylenes, and phosphines

The conversion-time data for 168 different Pd/Cu-catalyzed Sonogashira cross-coupling reactions of five arylacetylenes (phenylacetylene; 1-ethynyl-2-ethylbenzene; 1-ethynyl-2,4,6-R3-benzene (R = Me, Et, i-Pr)) and Me3SiCCH with seven