29872-25-1

Basic information

• Product Name: Piperidine, 1-(phenylmethyl)-, 1-oxide
• Synonyms: N-benzylpiperidine N-oxide;1-benzyl-piperidine-1-oxide;1-Benzyl-piperidin-1-oxid
• CAS NO: 29872-25-1
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 29872-25-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-(phenylmethyl)-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-(phenylmethyl)-, 1-oxide(29872-25-1)
• EPA Substance Registry System: Piperidine, 1-(phenylmethyl)-, 1-oxide(29872-25-1)

Safety Data

• Hazardous Substances Data: 29872-25-1(Hazardous Substances Data)

Upstream product

• 90524-27-9 Trifluoro-methanesulfonate1-(tert-butyl-dimethyl-silanyloxy)-1-methyl-piperidinium; 
• 17206-00-7 N-methylpiperidine-N-oxide 
• 2905-56-8 N-Benzylpiperidine 
• 100-39-0 benzyl bromide 
• 110-89-4 piperidine 

Downstream Products

• 100-52-7 benzaldehyde 
• 2905-56-8 N-Benzylpiperidine 
• 776-75-0 N-benzoylpiperidine 
• 46346-67-2 N-benzyloxypiperidine 
• 634878-89-0 2-allyl-1-benzylpiperidine 
• 122059-35-2 ethyl (1-benzylpiperidin-2-yl)acetate 
• 120153-68-6 N-benzylpiperidine-2-carbonitrile 

Relevant articles and documents

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Process for the preparation of amine oxides

The present invention provides a process for the preparation of amine oxide by reacting a tertiary or a secondary amine with hydrogen peroxide as an oxidant in the presence of a recyclable heterogeneous catalyst comprising a layered double hydroxide exchanged with an anion in the presence of an additive selected from the group consisting of benzonitrile, propionitrile, isoburyronitrile, benzamide and isobutyramide.

On the preparation of amine N-oxides by using dioxiranes

The reaction of heterocyclic aromatic amines, anilines and tertiary amines with dimethyldioxirane (DMD) was examined. Treatment of heterocyclic aromatic amines and anilines with a slight excess of DMD at 0°C afforded the corresponding N-oxides in quantitative conversion yields. In addition, the oxidation was chemoselective in the presence of carbon-carbon double bonds. On the other hand, most of the tertiary amines assayed did afford also quantitative yields of the corresponding N. oxides, although reaction conditions, in particular regarding the amount of DMD required, depended on each substrate. Additional studies carried out on selected substrates suggested that certain N-oxides derived from tertiary amines deactivate DMD.