30045-16-0

Basic information

• Product Name: Dehydrocorydaline
• Synonyms: Dehydrocorydaline;DEHYDROCORYDALINE98%;13-Methyl-2,3,9,10-tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium;5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium;13-Methylpalmatine;dehydeocorydaline;Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-
• CAS NO: 30045-16-0
• Molecular Formula: C22H24NO4
• Molecular Weight: 366.43000
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 30045-16-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 170-173℃
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: Orange Powder
• Density: g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: Dehydrocorydaline(CAS DataBase Reference)
• NIST Chemistry Reference: Dehydrocorydaline(30045-16-0)
• EPA Substance Registry System: Dehydrocorydaline(30045-16-0)

Safety Data

• Hazardous Substances Data: 30045-16-0(Hazardous Substances Data)

Usage

General Description

Dehydrocorydaline is a plant-based alkaloid primarily found in Corydalis yanhusuo, a traditional Chinese medicinal herb. It is known for its broad pharmacological properties such as analgesic and anti-inflammatory effects. It has been found to inhibit platelet aggregation, offering potential cardiovascular benefits. Dehydrocorydaline also demonstrates anti-cancer activities by triggering cell death pathways in cancer cells. Further, it possesses potential neuroprotective properties. However, while the substance shows promise, further research is needed to fully understand its capabilities and possible side effects.

InChI:InChI=1/C22H24NO4.ClH/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23;/h6-7,10-12H,8-9H2,1-5H3;1H/q+1;/p-1

Upstream product

• 7732-18-5 water 
• 518-69-4 corydaline 
• 64-17-5 ethanol 
• 7553-56-2 iodine 
• 7697-37-2 nitric acid 
• 6018-35-5 trans-(+-)-5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine 
• 53811-50-0 6-bromo-2,3-dimethoxybenzaldehyde 
• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 1600-27-7 mercury(II) diacetate 
• 64-19-7 acetic acid 

Downstream Products

• 518-69-4 mesocorydaline 

Relevant articles and documents

Method for synthesizing benzophenanthridine and protoberberine alkaloids through modular diversity regulation and control

The invention discloses a method for synthesizing benzophenanthridine and protoberberine alkaloids through modular diversity regulation and control. The method comprises the following steps: improving a substituent group of a high-iodine salt leaving group, generating pyridine alkyne under the action of relatively mild potassium tert-butoxide, and carrying out [4 + 2] cycloaddition reaction on the pyridine alkyne and diene to obtain polysubstituted isoquinoline ring precursor compounds. Ring opening and aromatization of the isoquinoline ring precursor are realized by developing a novel iridium-catalyzed cross-coupling method, polysubstituted isoquinoline ring compounds with connecting capacity are efficiently synthesized, and then the polysubstituted isoquinoline ring compounds are coupled with a high-activity polysubstituted cyclic boric acid to obtain 3-aryl isoquinoline high-grade intermediates. Through application of two different chemical principles, regulation and control of the 3-aryl isoquinoline high-grade intermediates are realized, and benzophenanthridine and protoberberine alkaloids are modularly, diversely and efficiently synthesized.

Coralydine composition and Hofmann decomposition. Corydaline, synthesis from palmatine by recent methods.

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