301846-11-7

Basic information

• Product Name: Ethyl 5-Amino-2-benzylthio-4-(3-thienyl)-thieno[2,3-d]pyrimidine-6-carboxylate
• CAS NO: 301846-11-7
• Molecular Weight: 427.572
• Mol File: 301846-11-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethyl 5-Amino-2-benzylthio-4-(3-thienyl)-thieno[2,3-d]pyrimidine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 5-Amino-2-benzylthio-4-(3-thienyl)-thieno[2,3-d]pyrimidine-6-carboxylate(301846-11-7)
• EPA Substance Registry System: Ethyl 5-Amino-2-benzylthio-4-(3-thienyl)-thieno[2,3-d]pyrimidine-6-carboxylate(301846-11-7)

Safety Data

• Hazardous Substances Data: 301846-11-7(Hazardous Substances Data)

Upstream product

• 498-62-4 3-thiophene carboxaldehyde 
• 623-51-8 ethyl 2-sulfanylacetate 
• 105-56-6 ethyl 2-cyanoacetate 
• 621-85-2 S-benzyl isothiocarbamide 

Relevant articles and documents

Bicyclic heteroamatic compounds useful as LH agonists

The invention relates to a bicyclic heteroaromatic derivative compound according to general formula (I), or a pharmaceutically acceptable salt thereof, wherein R1is NR5R6, OR5, SR5or R7; R5and R6are independently selected from H, (1-8C)alkyl, (2-8C)alkenyl, (2-8C)alkynyl, (3-8C)cycloalkyl, (2-7C)heterocycloalkyl, alkyl(1-8C)carbonyl, (6-14C)arylcarbonyl, (6-14C)aryl or (4-13C)heteroaryl, or R5and R6together are joined in a (2-7C)heterocloalkyl ring; R7is (3-8C)cycloalkyl, (2-7C)heterocycloalkyl, (6-14C)aryl or (4-13C)heteroaryl, R2is (1-8C)alkyl, (2-8C)alkenyl, (2-8C)alkynyl, or (6-14C)aryl or (4-13C)heteroaryl, both optionally substituted with one or more substituents selected from (1-8C)alkyl, (1-8C)alkylthio, (1-8C)(di)alkylamino, (1-8C)alkoxy, (2-8C)alkenyl, or (2-8C)alkynyl; R3is (1-8C)alkyl, (2-8C)alkenyl, (2-8C)alkynyl, (3-8C)cycloalkyl, (2-7C)heterocycloalkyl, or (6-14C)aryl or (4-13C)heteroaryl, both optionally substituted with one or more substituents selected from (1-8C)alkyl, (1-8C)(di)alkylamino or (1-8C)alkoxy; X is S, O or N(R4); R4is H, (1-8C)alkyl, (1-8C)alkylcarbonyl, (6-14C)arylcarbonyl or (6-14C)aryl(1-8C)alkyl; Y is CH or N; Z is NH2or OH; A is S, N(H), N(R9), O or a bond; R9can be selected from the same groups as described for R2and B is N(H), O or a bond. The compounds of the invention have LH receptor activating activity and can be used in fertility regulating therapies.