30392-41-7 Usage
Description
(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate, also known as Bitolterol methanesulfonate, is a complex organic compound with a unique chemical structure. It is a derivative of bitolterol, a prodrug that releases colterol upon activation by esterases in the lung. (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate is characterized by its beta-hydroxy and p-toluoyloxy groups, as well as its ammonium and methanesulfonate components. Bitolterol methanesulfonate is a beta2-adrenergic receptor agonist, which means it can selectively bind to and activate beta2-adrenergic receptors, leading to various physiological effects.
Uses
Used in Pharmaceutical Industry:
(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate is used as a bronchodilator for the relief of bronchospasm in conditions such as asthma, chronic bronchitis, and emphysema. Its beta2-selective agonist activity helps to relax the smooth muscles in the airways, leading to improved airflow and reduced symptoms of respiratory distress.
The N-t-butyl group in the compound enhances its beta2-selectivity, while the ester form is lipophilic, which helps to keep it localized in the lung and resistant to metabolism by catechol-O-methyltransferase (COMT). This contributes to an increased duration of action. The onset of action begins 2 to 4 minutes after administration, and the effect can last as long as 8 hours.
Additionally, bitolterol methanesulfonate has an adverse effect profile similar to that of other beta2-selective agonists, but with less drowsiness and restlessness compared to other direct-acting agonists. This makes it a valuable option for patients seeking relief from bronchospasm without experiencing significant side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 30392-41-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,3,9 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 30392-41:
(7*3)+(6*0)+(5*3)+(4*9)+(3*2)+(2*4)+(1*1)=87
87 % 10 = 7
So 30392-41-7 is a valid CAS Registry Number.
InChI:InChI=1/C28H31NO5.CH4O3S/c1-18-6-10-20(11-7-18)26(31)33-24-15-14-22(23(30)17-29-28(3,4)5)16-25(24)34-27(32)21-12-8-19(2)9-13-21;1-5(2,3)4/h6-16,23,29-30H,17H2,1-5H3;1H3,(H,2,3,4)