30457-12-6

Basic information

• Product Name: (1H-benzo[d][1,2,3]triazol-1-yl)(2-chlorophenyl)methanone
• Synonyms: (1H-benzo[d][1,2,3]triazol-1-yl)(2-chlorophenyl)methanone
• CAS NO: 30457-12-6
• Molecular Weight: 257.679
• Mol File: 30457-12-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (1H-benzo[d][1,2,3]triazol-1-yl)(2-chlorophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-benzo[d][1,2,3]triazol-1-yl)(2-chlorophenyl)methanone(30457-12-6)
• EPA Substance Registry System: (1H-benzo[d][1,2,3]triazol-1-yl)(2-chlorophenyl)methanone(30457-12-6)

Safety Data

• Hazardous Substances Data: 30457-12-6(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 118-91-2 ortho-chlorobenzoic acid 
• 609-65-4 o-chlorobenzoyl chloride 

Downstream Products

• 98191-99-2 2-(2-chlorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 49672-22-2 2-(2-chlorophenyl)-4,5-dihydro-1,3-thiazole 
• 1260613-35-1 (2-oxoimidazolidin-1,3-diyl)bis((2-chlorophenyl)methanone) 
• 67357-53-3 1-(2-chlorobenzoyl)imidazolidin-2-one 
• 1043910-14-0 3-demethoxycarbonyl-3-(2'-chlorobenzoylamino)methylvindoline 
• 1043910-84-4 C₅₂H₆₀ClN₅O₇ 
• 49747-51-5 o-chlorobenzoyl azide 
• 62247-17-0 2-chlorobenzenecarboselenoic acid Se-phenyl ester 
• 13208-19-0 N,N'-bis(2-chlorophenyl)urea 
• 1263913-95-6 2-(2-chlorobenzoylamido)phenylphosphonic acid diethyl ester 
• 95460-99-4 N-((2-chlorophenyl)carbamoyl)benzamide 

Relevant articles and documents

Acyloxyphosphonium versus aminophosphonium intermediates: Application to the synthesis of N-acylbenzotriazoles

In attempts to convert carboxylic acids directly into N-acylbenzotriazoles by using Ph3P/I2 as an acid-activating system, the outcome of the reaction is reversed from no reaction to almost quantitative yield of the expected product simply by switching the order of the addition of the reagents to the presumed acyloxyphosphonium intermediate. If triethylamine was present before treatment with 1H-benzotriazole, anhydride was always exclusively generated without a detectable amount of the expected product. However, if the base was applied after the addition of 1H-benzotriazole, the reaction proceeded smoothly to afford N-acylbenzotriazoles in good to excellent yields within short reaction times. 31P NMR spectroscopy revealed the presence of a benzotriazophosphonium species in preventing the formation of the anhydride by attack of the carboxylate anion at the acyl function of the acyloxyphosphonium salt.

Trichloroisocyanuric Acid Mediated High-Yielding Synthesis of N -Acylbenzotriazoles under Mild Reaction Conditions

N -Acylbenzotriazoles are achieved in good yields from the corresponding carboxylic acids by using only 0.35 equivalent of trichloroisocyanuric acid and 1.2 equivalents of PPh 3. The salient features of the developed reaction path include an ec

Visible-Light-Induced C(sp2)-P Bond Formation by Denitrogenative Coupling of Benzotriazoles with Phosphites

A visible-light-induced denitrogenative phosphorylation of benzotriazoles is presented, in which diverse substituted aryl phosphonates could be obtained in good to excellent yields. This efficient protocol exhibits good tolerance with various functional g