311343-00-7Relevant articles and documents
NAC/MEA conjugate: A new potent antioxidant which increases the GSH level in various cell lines
Oiry, Joel,Mialocq, Patricia,Puy, Jean Y.,Fretier, Philippe,Clayette, Pascal,Dormont, Dominique,Imbach, Jean L.
, p. 1189 - 1191 (2001)
I-152 is a prodrug of NAC and MEA with potent pro-GSH effects in human macrophages, astrocytes and lymphocytes. This molecule could be of interest in HIV infection in respect to its antioxidant and anti-HIV activities, but also in other diseases to counte
Novel antioxidants, preparation processes and their uses
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Page 12, (2010/02/08)
The invention concerns a process for preparing compounds of general formula (I) wherein R and R′ represent an alkyl radical or an aryl group; and R″ is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and wherein these compounds are or not in the thiazolidine form; by protecting the N-acyl-L-cysteine to form an intermediate compound; and then by coupling said intermediate compound with S-acylcysteamine hydrochloride or with thiazolidine.