315203-51-1

Basic information

• Product Name: PIPERIDIN-4-YLIDENE-ACETIC ACID ETHYL ESTER
• Synonyms: PIPERIDIN-4-YLIDENE-ACETIC ACID ETHYL ESTER;ethyl 2-piperidin-4-ylideneacetate
• CAS NO: 315203-51-1
• Molecular Formula: C₉H₁₅NO₂
• Molecular Weight: 169.22
• Mol File: 315203-51-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PIPERIDIN-4-YLIDENE-ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: PIPERIDIN-4-YLIDENE-ACETIC ACID ETHYL ESTER(315203-51-1)
• EPA Substance Registry System: PIPERIDIN-4-YLIDENE-ACETIC ACID ETHYL ESTER(315203-51-1)

Safety Data

• Hazardous Substances Data: 315203-51-1(Hazardous Substances Data)

Usage

InChI:InChI=1S/C9H15NO2/c1-2-12-9(11)7-8-3-5-10-6-4-8/h7,10H,2-6H2,1H3

Upstream product

• 82244-11-9 ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Relevant articles and documents

Pd/C(en)-catalyzed chemoselective hydrogenation with retention of the N-Cbz protective group and its scope and limitations

A chemoselective method for the hydrogenation of acetylene, olefin, azide, nitro and benzyl ester functionalities with retention of the aliphatic N-Cbz group was established. The chemoselectivity was accomplished by using a combination of 5% Pd/C-ethylenediamine [5% Pd/C(en)] and THF (or 1,4-dioxane) as a solvent, and the scope and limitations of this methodology were investigated. These results reinforce the utility of N-Cbz protective groups in synthetic chemistry, especially in peptide synthesis. (C) 2000 Elsevier Science Ltd.