315229-51-7Relevant articles and documents
Synthesis of chiral piperazinones as versatile scaffolds for peptidomimetics
Rübsam, Frank,Mazitschek, Ralph,Giannis, Athanassios
, p. 8481 - 8487 (2000)
Chiral piperazinones were synthesized as conformationally restricted peptidomimetics starting from inexpensive and readily available D-glucosamine hydrochloride and amino acid methyl esters. Different synthetic strategies are devised to allow attachment of side chains imitating the parent peptide as shown for the RGD motif. (C) 2000 Elsevier Science Ltd.