315712-26-6

Basic information

• Product Name: N-(4-methoxyphenyl)-cyclohexanecarboxamide
• Synonyms: N-(4-methoxyphenyl)-cyclohexanecarboxamide
• CAS NO: 315712-26-6
• Molecular Weight: 233.31
• Mol File: 315712-26-6.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: N-(4-methoxyphenyl)-cyclohexanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-cyclohexanecarboxamide(315712-26-6)
• EPA Substance Registry System: N-(4-methoxyphenyl)-cyclohexanecarboxamide(315712-26-6)

Safety Data

• Hazardous Substances Data: 315712-26-6(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 98-89-5 Cyclohexanecarboxylic acid 
• 100-17-4 para-methoxynitrobenzene 
• 401-75-2 trifluoromethylcyclohexane 
• 201230-82-2 carbon monoxide 
• 626-62-0 Cyclohexyl iodide 
• 110-82-7 cyclohexane 
• 10349-38-9 p-methoxyphenylisonitrile 
• 7472-54-0 N-(p-methoxyphenyl)benzamide 
• 80998-63-6 cyclohexyl(1H-indol-1-yl)methanone 
• 5416-93-3 4-Methoxyphenyl isocyanate 
• 13939-06-5 molybdenum hexacarbonyl 
• 696-62-8 para-iodoanisole 
• 1122-56-1 cyclohexylcarboxamide 

Downstream Products

• 1262796-64-4 C₂₄H₂₅NO₂ 
• 1192739-77-7 4-bromo-2-cyclohexyl-6-methoxyquinazoline 

Relevant articles and documents

Method for synthesizing amide derivative under catalysis of vanadium

The invention discloses a method for synthesizing an amide derivative under the catalysis of vanadium, which comprises the following step of: by using a nitro aromatic compound and an ester compound as raw materials, a vanadium compound as a catalyst and magnesium chips as a reducing agent, carrying out amidation reaction in an organic solvent to obtain the amide derivative. The method has the advantages that (1) the nitro aromatic compound which is good in stability, low in price and easy to obtain is used as a nitrogen source; (2) the used catalyst is cheap, easy to obtain and low in toxicity; and (3) the method has good substrate applicability, and is suitable for aromatic nitro compounds, fatty esters and aryl esters containing different substituents.

Tandem Photoredox Catalysis: Enabling Carbonylative Amidation of Aryl and Alkylhalides

We report a new visible-light-mediated carbonylative amidation of aryl, heteroaryl, and alkyl halides. A tandem catalytic cycle of [Ir(ppy)2(dtb-bpy)]+ generates a potent iridium photoreductant through a second catalytic cycle in the presence of DIPEA, which productively engages aryl bromides, iodides, and even chlorides as well as primary, secondary, and tertiary alkyl iodides. The versatile in situ generated catalyst is compatible with aliphatic and aromatic amines, shows high functional-group tolerance, and enables the late-stage amidation of complex natural products.

Nickel/Briphos-Catalyzed Direct Transamidation of Unactivated Secondary Amides Using Trimethylsilyl Chloride

Direct transamidation of secondary amides was developed via nickel catalysis. In the presence of trimethylsilyl chloride and manganese, Ni(diglyme)Cl2 with a Briphos ligand efficiently promoted the transamidation of N-aryl benzamide derivatives with primary amines to afford the corresponding secondary amides in moderate to good yields. Primary amines bearing electron-donating groups gave higher yields of the transamidation products.