3194-15-8Relevant articles and documents
-
Emling et al.
, p. 703 (1949)
-
Manganese PNP-pincer catalyzed isomerization of allylic/homo-allylic alcohols to ketones-activity, selectivity, efficiency
Xia, Tian,Spiegelberg, Brian,Wei, Zhihong,Jiao, Haijun,Tin, Sergey,Hinze, Sandra,De Vries, Johannes G.
, p. 6327 - 6334 (2019/11/20)
We report the first manganese catalyzed isomerization of allylic alcohols to produce the corresponding carbonyl compounds. The ligand plays a decisive role in the efficiency of this reaction. Very high conversions could be obtained using a solvent-free reaction system. A detailed DFT study reveals a self-dehydrogenation/hydrogenation reaction mechanism which was verified by the isolation of the α,β-unsaturated ketone as intermediate and a deuterium labeling experiment. It also provided a rationale for the observed selectivity and the higher efficiency of phenyl over isopropyl substitution.
Method for preparing 2-acyl furan
-
Paragraph 0024; 0027, (2019/12/25)
The invention relates to a method for preparing 2-acyl furan. The method is characterized by comprising the following steps: (1) controlling the temperature to -10-40 DEG C, and adding 70-98% of a water phase or 10-90% of a mixed liquid of the water phase and an organic phase, 0.0001-2.0% of an osmium compound and 0.001-5.0% of an amine compound into a reaction container so as to obtain a reactionliquid; (2) feeding the reaction liquid into a sealed reactor, and performing gas exchange to provide an aerobic environment for reactions; (3) adding 1-(2-furyl)-1-alkyl methanol into the sealed reactor, and controlling the pressure to 0-20MPa and the temperature to 0-200 DEG C for 1-74 hours; and (4) after the reaction is stopped, performing cooling to the room temperature, performing pressurerelease to the barometric pressure, adding sodium hydrogen sulfate and acetic acid, performing extraction, and performing organic phase vacuum distillation refining, so as to obtain a 2-acyl furan product. The method has the advantages that technical and economical defects of a conventional synthesis route can be avoided, process procedures can be reduced, consumption and emission can be reduced,the energy consumption and the cost can be lowered, and the method is applicable to capacity increase industrial production.
