325464-63-9

Basic information

• Product Name: benzyl N-Boc-Tra-D,L-m-Tyr(O-2-Pyrim)-m-aminobenzoate
• Synonyms: benzyl N-Boc-Tra-D,L-m-Tyr(O-2-Pyrim)-m-aminobenzoate
• CAS NO: 325464-63-9
• Molecular Weight: 707.827
• Mol File: 325464-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl N-Boc-Tra-D,L-m-Tyr(O-2-Pyrim)-m-aminobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N-Boc-Tra-D,L-m-Tyr(O-2-Pyrim)-m-aminobenzoate(325464-63-9)
• EPA Substance Registry System: benzyl N-Boc-Tra-D,L-m-Tyr(O-2-Pyrim)-m-aminobenzoate(325464-63-9)

Safety Data

• Hazardous Substances Data: 325464-63-9(Hazardous Substances Data)

Upstream product

• 263272-46-4 C₁₈H₃₁NO₆ 
• 27687-14-5 trans 4-(tert-butyloxycarbonylamino)methylcyclohexanecarboxylic acid 

Relevant articles and documents

Development of potent and selective plasmin and plasma kallikrein inhibitors and studies on the structure-activity relationship

Based on structure-activity relationship studies, we designed and synthesized plasmin (PL) and plasma kallikrein (PK) inhibitors. Trans-(4-aminomethylcyclohexanecarbonyl)-Tyr(O-PIC)-octylamide inhibited PL, PK, urokinase (UK) and thrombin (TH) with IC50 values of 0.53, 30, 5.3 and >400 μM, respectively. Trans-(4-aminomethylcyclohexanecarbonyl)-Tyr(O-2-Pyrim)-4-carboxyanilide inhibited PL, PK, UK and TH with IC50 values of 36, 0.56, 440 and >1000 μM, respectively.