32902-85-5Relevant articles and documents
IMIDAZOLE AS LEAVING GROUP IN AROMATIC NUCLEOPHILIC SUBSTITUTION REACTIONS
Vargas, Elba B. de,Rossi, Rita H. de
, p. 4423 - 4426 (1982)
The reaction of N-(2,4,6-trinitrophenyl) imidazole with n-butylamine is pH dependent.A mechanism involving acid catalyzed leaving group departure is suggested.
Kinetics of snar reactions of 1-phenoxy-nitrobenzenes with aliphatic amines in toluene: Ring substituent and solvent effects on reaction pathways
Isanbor, Chukwuemeka,Babatunde, Alice Ibitola
experimental part, p. 1078 - 1085 (2010/07/13)
Rate constants are reported for the reactions of a series of 4-substituted-1-phenoxy-2,6-dinitrobenzenes 1 and 6-substituted-1-phenoxy-2,4- dinitrobenzenes 2 activated by CF3, COOCH3, CN, NO 2 groups or by ring-nitrogen wi
Nucleophilic aromatic substitution for heteroatoms: An oxidative electrochemical approach
Gallardo, Iluminada,Guirado, Gonzalo,Marquet, Jordi
, p. 2548 - 2555 (2007/10/03)
The nucleophilic aromatic substitution for heteroatom through electrochemical oxidation of the intermediate σ-complexes (Meisenheimer complexes) in simple nitroaromatic compounds is reported for the first time (NASX process). The studies have been carried out with hydride, cyanide, fluoride, methoxy, and ethanethiolate anions and n-butylamine as a nucleophile, at the cyclic voltammetry (CV) and preparative electrolysis level. The cyclic voltammetry experiments allow for detection and characterization of the σ-complexes and they have led us to a proposal for the mechanism of the oxidation step. Furthermore, the power of the CV technique in the analysis of the reaction mixture throughout the whole chemical and electrochemical process is described.