330785-84-7 Usage
Description
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]is a complex organic compound with a unique molecular structure. It is characterized by its pyrimidine and pyrrolidine rings, as well as a chloro-methoxybenzyl group attached to the amino function. 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)1-pyrrolidinyl]serves as an intermediate in the synthesis of pharmaceuticals, specifically in the preparation of Avanafil (A794670).
Uses
Used in Pharmaceutical Industry:
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]is used as a key intermediate in the synthesis of Avanafil (A794670) for the treatment of erectile dysfunction. Avanafil is a phosphodiesterase (PDE5) inhibitor that works by increasing blood flow to the penis, thus helping men achieve and maintain an erection.
As an intermediate in the synthesis of Avanafil, this compound plays a crucial role in the development of a medication that addresses a common health issue affecting a significant portion of the male population. 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)1-pyrrolidinyl]-'s unique structure allows for the formation of Avanafil, which has demonstrated efficacy in treating erectile dysfunction with a lower risk of side effects compared to other PDE5 inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 330785-84-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,0,7,8 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 330785-84:
(8*3)+(7*3)+(6*0)+(5*7)+(4*8)+(3*5)+(2*8)+(1*4)=147
147 % 10 = 7
So 330785-84-7 is a valid CAS Registry Number.
330785-84-7Relevant articles and documents
A kind of avanafil impurity D and synthesis method and application thereof
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Paragraph 0017; 0023, (2022/01/12)
The present invention provides a new aphranarfil impurity and synthesis method thereof, by synthesizing and characterizing the impurity, the structure of the impurity is determined, the drug impurity profile of avanafil is perfected, the resulting product is of high purity, can be used as a control for drug quality control research.
Method of preparing medical compound stendra
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Paragraph 0014; 0035-0036; 0046-0047; 0057-0058, (2019/02/04)
The invention discloses a method of preparing a medical compound stendra and belongs to the technical field of medical compounds. The key point of the technical scheme is as follows: the synthetic route of the method of preparing the medical compound stendra is as follows: a formula as shown in the description. The method has the advantages of being high in yield, low in cost, economical and environment-friendly, suitable for industrialization, high in product impurity and the like, and is a synthetic method which has industrial production value.
Atorvastatin that non-preparation method
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Paragraph 0073-0075, (2017/07/01)
The invention relates to a preparation method of avanafil and a new compound provided in a preparation process. According to the method, 5-uracil carboxylic acid or an ester thereof is taken as the raw material, and the avanafil meeting the clinical requirements can be synthesized at a relatively cost; besides, the preparation method is simple and convenient to operate, mild in reaction conditions, high in yield, low in cost, environmentally friendly and suitable for industrial large-scale production of the avanafil.