33289-85-9

Basic information

• Product Name: dipsacoside B
• Synonyms: dipsacoside B;BRS013840;(3beta,4alpha)-3-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid, 6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl ester;Glycoside L-G3;Dipsacoside B(Glycoside L-G3);Tauroside G3;Dipsacoside B, 98%, from Lonicera confusa (Sweet) DC.
• CAS NO: 33289-85-9
• Molecular Formula: C₅₃H₈₆O₂₂
• Molecular Weight: 1075.24
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 33289-85-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.46
• Refractive Index: 1.632
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.50±0.70(Predicted)
• CAS DataBase Reference: dipsacoside B(CAS DataBase Reference)
• NIST Chemistry Reference: dipsacoside B(33289-85-9)
• EPA Substance Registry System: dipsacoside B(33289-85-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 33289-85-9(Hazardous Substances Data)

Usage

Description

Dipsacoside B is a cytotoxic biactive saponin that is naturally derived from the buds of the Lonicera macranthides plant. It possesses potent cytotoxic properties, making it a valuable compound for various applications in the pharmaceutical and related industries.

Uses

Used in Pharmaceutical Industry:
Dipsacoside B is used as a cytotoxic agent for its ability to inhibit the growth and proliferation of cancer cells. It has demonstrated potential in targeting various types of cancer, including solid tumors, due to its natural cytotoxic properties.
Used in Drug Development:
Dipsacoside B is utilized as a key component in the development of novel anticancer drugs. Its cytotoxic nature allows researchers to explore its potential in creating new therapeutic options for cancer treatment, either as a standalone agent or in combination with other chemotherapeutic drugs.
Used in Cancer Research:
In the field of cancer research, Dipsacoside B serves as a valuable tool for studying the mechanisms of cancer cell growth and apoptosis. Its cytotoxic properties make it an important compound for investigating the underlying pathways involved in cancer progression and identifying potential targets for therapeutic intervention.
Used in Drug Delivery Systems:
Similar to gallotannin, Dipsacoside B can also be incorporated into drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. Researchers are exploring the use of various organic and metallic nanoparticles as carriers for Dipsacoside B, aiming to improve its overall effectiveness in cancer treatment.

InChI:InChI=1/C53H86O22/c1-23-32(57)36(61)40(65)44(70-23)74-42-33(58)26(56)20-68-46(42)73-31-11-12-49(4)29(50(31,5)22-55)10-13-52(7)30(49)9-8-24-25-18-48(2,3)14-16-53(25,17-15-51(24,52)6)47(67)75-45-41(66)38(63)35(60)28(72-45)21-69-43-39(64)37(62)34(59)27(19-54)71-43/h8,23,25-46,54-66H,9-22H2,1-7H3/t23-,25?,26-,27+,28+,29?,30?,31-,32-,33-,34+,35+,36+,37-,38-,39+,40+,41+,42+,43+,44-,45-,46-,49-,50-,51+,52+,53-/m0/s1

Upstream product

• 120481-41-6 3-O-<α-L-rhamnopyranosyl(1->2)-α-L-arabinopyranosyl>-28-O-<6-acetyl-β-D-glucopyranosyl(1->6)-β-D-glucopyranosyl>hederagenin 
• 14216-03-6 HN-saponin P 
• 97240-03-4 hederagenin-3-O-α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1->4)-O-6-O-acetyl-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl ester 

Downstream Products

• 27013-91-8 α-Hederin 
• 27013-91-8 alpha-Hederin 

Relevant articles and documents

Studies on the saponins of Lonicera japonica THUNB.

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